Robert Silber
Harvard University
5 Papers
171 Citations
Robert Silber is an academic researcher from Harvard University. The author has contributed to research in topics: Phosphatidylinositol & Hairy Cell. The author has an hindex of 4, co-authored 5 publications. Previous affiliations of Robert Silber include New York University.
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Papers
Deficiency of lymphocyte function-associated antigen 3 (LFA-3) in paroxysmal nocturnal hemoglobinuria. Functional correlates and evidence for a phosphatidylinositol membrane anchor.
TL;DR: It is confirmed that LFA-3 is a cell adhesion molecule that mediates adhesion by interacting with CD2 antigen and is attached to the cell membrane by a phosphatidylinositol glycolipid moiety.
Electrophoretic mobility distributions distinguish hairy cells from other mononuclear blood cells and provide evidence for the heterogeneity of normal monocytes.
Howard R. Petty,Howard R. Petty,B. R. Ware,B. R. Ware,Leonard F. Liebes,Leonard F. Liebes,E. Pelle,E. Pelle,Robert Silber,Robert Silber +9 more
TL;DR: The hairy cell possesses a distinct pattern of surface charge properties that clearly distinguish it from the circulating B cells, T cells, or monocytes, and hence differs from that or normal and CLL lymphocytes before, and from that of monocytes after, treatment with neuraminidase.
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Studies on the succinylation of erythrocyte membranes.
Charles F. Moldow,Charles F. Moldow,Dorothea Zucker-Franklin,Dorothea Zucker-Franklin,Adrienne S. Gordon,Adrienne S. Gordon,Verne D. Hospelhorn,Verne D. Hospelhorn,Robert Silber,Robert Silber +9 more
TL;DR: The results indicate that succinylation is associated with a decrease in ordered structure of the protein, which is related to the ABO blood group antigens and phytohemagglutinin binding activity.
16
The major Fc receptor in blood has a phosphatidylinositol anchor and is deficient in paroxysmal nocturnal haemoglobinuria.
TL;DR: The findings on the FcγR III raise the question of how a PIG-tailed protein important in immune complex clearance in vivo and in antibody-dependent killing mediates ligand internalization and cytotoxicity.