Robert N. Baldassano
Children's Hospital of Philadelphia
347 Papers
1.4K Citations
Robert N. Baldassano is an academic researcher from Children's Hospital of Philadelphia. The author has contributed to research in topics: Inflammatory bowel disease & Medicine. The author has an hindex of 72, co-authored 301 publications. Previous affiliations of Robert N. Baldassano include Seattle Children's & University of California, Los Angeles.
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Papers
Factors associated with early outcomes following standardised therapy in children with ulcerative colitis (PROTECT): a multicentre inception cohort study
Jeffrey S. Hyams,Sonia M. Davis,David R. Mack,Brendan M. Boyle,Anne M. Griffiths,Neal S. Leleiko,Cary G. Sauer,David J. Keljo,James Markowitz,Susan S. Baker,Joel R. Rosh,Robert N. Baldassano,Ashish S. Patel,Marian Pfefferkorn,Anthony Otley,Melvin B. Heyman,Joshua D. Noe,Maria Oliva-Hemker,Paul A. Rufo,Jennifer A. Strople,David Ziring,Stephen L. Guthery,Boris Sudel,Keith J. Benkov,Prateek Wali,Dedrick E. Moulton,Jonathan Evans,Michael D. Kappelman,Alison Marquis,Francisco A. Sylvester,Margaret H. Collins,Suresh Venkateswaran,Marla Dubinsky,Vin Tangpricha,Krista Spada,Ashley Britt,Bradley Saul,Nathan Gotman,Jessie Wang,Jose Serrano,Subra Kugathasan,Thomas D. Walters,Lee A. Denson +42 more
TL;DR: The findings provide guidelines to assess response of children newly diagnosed with UC to standardized initial therapy and identify predictors of treatment response and failure and suggest that additional therapeutic interventions may be warranted to improve early outcomes.
Early Response to Treatment with Adalimumab in Children with Moderately to Severely Active Crohnʼs Disease: Results from IMAgINE 1: 2048
Jaroslaw Kierkus,Wallace Crandall,Jeffrey S. Hyams,Joel R. Rosh,James Markowitz,Robert N. Baldassano,Andreas Lazar,Yaqin Wang,Samantha Eichner,Roopal Thakkar +9 more
Detecting Microbial Dysbiosis Associated with Pediatric Crohn Disease Despite the High Variability of the Gut Microbiota
Feng Wang,Jess L. Kaplan,Benjamin D. Gold,Manoj Bhasin,Naomi L. Ward,Richard Kellermayer,Barbara S. Kirschner,Melvin B. Heyman,Scot E. Dowd,Stephen B. Cox,Haluk Dogan,Blaire Steven,George D. Ferry,Stanley A. Cohen,Robert N. Baldassano,Christopher J. Moran,Elizabeth A. Garnett,Lauren Drake,Hasan H. Otu,Leonid A. Mirny,Towia A. Libermann,Harland S. Winter,Kirill S. Korolev +22 more
TL;DR: In this paper, a set of techniques based on population dynamics and information theory was developed to identify additional bacterial taxa associated with pediatric Crohn disease and can detect significant changes in microbial communities with fewer samples than previous statistical approaches required.
Characterization of Genetic Loci That Affect Susceptibility to Inflammatory Bowel Diseases in African Americans
Chengrui Huang,Talin Haritunians,David T. Okou,David J. Cutler,Michael E. Zwick,Kent D. Taylor,Lisa W. Datta,Joseph C. Maranville,Zhenqiu Liu,Shannon E. Ellis,Pankaj Chopra,Jonathan Steven Alexander,Robert N. Baldassano,Raymond K. Cross,Themistocles Dassopoulos,Tanvi Dhere,Richard H. Duerr,John S. Hanson,Jason K. Hou,Sunny Z. Hussain,Kim L. Isaacs,Kelley E Kachelries,Howard A. Kader,Michael D. Kappelman,Jeffrey Katz,Richard Kellermayer,Barbara S. Kirschner,John F. Kuemmerle,Archana Kumar,John H. Kwon,Mark Lazarev,Peter J. Mannon,Dedrick E. Moulton,Bankole O. Osuntokun,Ashish S. Patel,John D. Rioux,Jerome I. Rotter,Shehzad Ahmed Saeed,Ellen Scherl,Mark S. Silverberg,Ann L. Silverman,Stephan R. Targan,John F. Valentine,Ming-Hsi Wang,Claire L. Simpson,S. Louis Bridges,Robert P. Kimberly,Stephen S. Rich,Judy H. Cho,Anna Di Rienzo,Linda W. H. Kao,Dermot P.B. McGovern,Steven R. Brant,Subra Kugathasan +53 more
TL;DR: In a genetic analysis of 3308 AA IBD cases and controls, it was found that many variants associated with IBD in Caucasians also showed association evidence with these diseases in AAs; the complex genetic factors that determine risk for or protection against I BD in different populations require further study.
Long ncRNA Landscape in the Ileum of Treatment-Naive Early-Onset Crohn Disease
Yael Haberman,Yael Haberman,Marina BenShoshan,Marina BenShoshan,Ayelet Di Segni,Phillip J. Dexheimer,Tzipi Braun,Batia Weiss,Batia Weiss,Thomas D. Walters,Robert N. Baldassano,Joshua D. Noe,James Markowitz,Joel R. Rosh,Melvin B. Heyman,Anne M. Griffiths,Wallace Crandall,David R. Mack,Susan S. Baker,Richard Kellermayer,Ashish S. Patel,Anthony R. Otley,Steven J. Steiner,Ajay S. Gulati,Stephen L. Guthery,Neal S. LeLeiko,Dedrick E. Moulton,Barbara S. Kirschner,Scott B. Snapper,Camila Avivi,Iris Barshack,Iris Barshack,Maria Oliva-Hemker,Stanley A. Cohen,David Keljo,David Ziring,Yair Anikster,Yair Anikster,Bruce J. Aronow,Jeffrey S. Hyams,Subra Kugathasan,Lee A. Denson +41 more
TL;DR: LncRNA utility is shown to correctly classify disease or healthy states and demonstrate their regulation in response to an inflammatory signal, showing these lncRNAs may serve as potential new tissue-specific targets for RNA-based interventions.