Robert N. Baldassano
Children's Hospital of Philadelphia
347 Papers
1.4K Citations
Robert N. Baldassano is an academic researcher from Children's Hospital of Philadelphia. The author has contributed to research in topics: Inflammatory bowel disease & Medicine. The author has an hindex of 72, co-authored 301 publications. Previous affiliations of Robert N. Baldassano include Seattle Children's & University of California, Los Angeles.
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Papers
Children with early-onset inflammatory bowel disease (IBD): analysis of a pediatric IBD consortium registry.
Melvin B. Heyman,Barbara S. Kirschner,Benjamin D. Gold,George D. Ferry,Robert N. Baldassano,Stanley A. Cohen,Harland S. Winter,Patricia Fain,Chris S. King,Terry J. Smith,Hashem B. El-Serag +10 more
TL;DR: This demographically diverse pediatric IBD cohort revealed age-related variation in the distribution of IBD phenotype, with a high prevalence of isolated colonic disease in young children.
Stratification of Risk of Progression to Colectomy in Ulcerative Colitis using Measured and Predicted Gene Expression
Angela Mo,Sini Nagpal,Kyle Gettler,Talin Haritunians,Mamta Giri,Yael Haberman,Yael Haberman,Rebekah Karns,Jarod Prince,Dalia Arafat,Nai Yun Hsu,Ling-Shiang Chuang,Carmen Argmann,Andrew Kasarskis,Mayte Suárez-Fariñas,Nathan Gotman,Emebet Mengesha,Suresh Venkateswaran,Paul A. Rufo,Susan S. Baker,Cary G. Sauer,James Markowitz,Marian Pfefferkorn,Joel R. Rosh,Brendan M. Boyle,David R. Mack,Robert N. Baldassano,Sapana Shah,Neal S. LeLeiko,Melvin B. Heyman,Anne M. Griffiths,Ashish S. Patel,Joshua D. Noe,Sonia Davis Thomas,Bruce J. Aronow,T Walters,Dermot P.B. McGovern,Jeffrey S. Hyams,Subra Kugathasan,Judy H. Cho,Lee A. Denson,Greg Gibson +41 more
TL;DR: In this article, the authors demonstrate that both measured and polygenic predicted gene expression (PPTRS) can identify ulcerative colitis patients at 5-fold elevated risk of colectomy with data from the PROTECT clinical trial and UK Biobank population cohort studies, independently replicated in an NIDDK-IBDGC dataset.
Induction and Maintenance Therapy With Infliximab for Children With Moderate to Severe Ulcerative Colitis
Jeffrey S. Hyams,Lakshmi Damaraju,Marion Blank,Jewel Johanns,Cynthia Guzzo,Harland S. Winter,Subra Kugathasan,Stanley N. Cohen,James Markowitz,Johanna C. Escher,Gigi Veereman Wauters,Wallace Crandall,Robert N. Baldassano,Anne M. Griffiths +13 more
TL;DR: Infliximab was safe and effective, inducing a response at week 8 in 73.3% of pediatric patients with moderate to severely active UC who did not respond to conventional therapy and maintaining benefit at week 54, assuming the more effective q8w remission rate.
Inflammatory bowel disease in African American children compared with other racial/ethnic groups in a multicenter registry.
Jolanda M. White,Siobhán O'Connor,Harland S. Winter,Melvin B. Heyman,Barbara S. Kirschner,George D. Ferry,Stanley A. Cohen,Robert N. Baldassano,Terry Smith,Traci Clemons,Benjamin D. Gold +10 more
TL;DR: Racial/ethnic differences in the epidemiology of IBD, particularly Crohn's disease, among American youths require further investigation.
Baseline terminal ileal CT and MRI measurements are associated with imaging outcomes in pediatric Crohn's disease: a cohort study.
Allison D Ta,J. Dillman,Nicholas J Ollberding,Yael Haberman,Robert N. Baldassano,James Markowitz,Anthony R. Otley,Jennifer L Dotson,Marian Pfefferkorn,Jeffrey S Hyams,Melvin B Heyman,Sandra C Kim,Joshua Noe,Scott B Snapper,A. Alazraki,Subramaniam Kugathasan,Lee A Denson +16 more
TL;DR: This cohort study of 96 pediatric Crohn's disease patients found baseline terminal ileal measurements, including minimum lumen diameter and bowel wall thickness, were associated with imaging outcomes, but not clinical response, at follow-up.