An improved ophthalmic instrument for in-vivo examination of a human eye including a wavefront sensor that estimates aberrations in reflections of the light formed as an image on the retina of the human eye and a phase compensator that spatially modulates the phase of incident light to compensate for the aberrations estimated by the wavefront sensor Optical elements create an image of a fixation target at the phase compensator, which produces a compensated image of the fixation target that compensates for aberrations estimated by the wavefront sensor. The compensated image of the fixation target produced by the phase compensator is recreated at the human eye to thereby provide the human eye with a view of compensation of the aberrations the human eye as estimated by the wavefront sensor. The phase compensator preferably comprises a variable focus lens that compensates for focusing errors and a deformable mirror that compensates for higher order aberrations. The optical elements preferably comprise a plurality of beam splitters and a plurality of lens groups each functioning as an afocal telescope. In addition, instruments and systems are provided that exploit these capabilities to enable efficient prescription and/or dispensing of corrective optics (e.g., contact lens and glasses).

Ophthalmic instrument with adaptive optic subsystem that measures aberrations (including higher order aberrations) of a human eye and that provides a view of compensation of such aberrations to the human eye

A method of forming a periodic array of nano-scale objects using a block copolymer, and nano-scale object arrays formed from the method are provided. The method for forming the arrays generally includes the steps of depositing a block copolymer of at least two blocks on a substrate to form an ordered meso-scale structured array of the polymer materials, forming catalytic metal dots based on the meso-scale structure, and growing nano-scale objects on the catalytic dots to form an ordered array of nano-scale objects.

Method of producing regular arrays of nano-scale objects using nano-structured block-copolymeric materials

A lens for correcting human vision, for example an IOL, contact lens or corneal inlay or onlay, that carries and interior phase or layer comprising a pattern of individual transparent adaptive displacement structures. In one embodiment, the displacement structures are actuated by a shape memory polymer (SMP) material or other polymer that is adjustable in shape in response to applied energy. The SMP can be designed to be selectively adjustable in volumetric dimension, modulus of elasticity and/or permeability. The adaptive optic means of the invention can he used to create highly localized surface corrections in the lens to correct higher order aberrations-which types of surfaces cannot be fabricated into and IOL and then implanted. The system of displacement structures also can provide spherical corrections in the lens.

Adaptive optic lens system and method of use

In the disclosed registration and authentication scheme, in the case of carrying out the registration and authentication of a wireless terminal with respect to a wireless base station provided inside the home, for example, a user of the wireless terminal must directly operate the wireless base station. For this reason, it is possible to prevent the registration and authentication of a wireless terminal of an external user who cannot easily operate the wireless base station, and thereby it is possible to realize the secure and easy registration and authentication processing even when the wireless communications are used.

Scheme for registration and authentication in wireless communication system using wireless LAN

An improved method for treating the eye includes the step of providing an ophthalmic instrument including an integral wavefront sensor. The wavefront sensor measures phase aberrations in reflections directed thereto to characterize aberrations of the eye. The wavefront sensor may be operably coupled to a display device, which displays a graphical representation of the aberrations of the eye. Such graphical representation may include: two dimensional contour maps that graphically depict contribution of pre-specified terms (such as spherical aberration, astigmatism and coma) for the aberrations of the eye, coefficients corresponding to such pre-specified terms that characterize the aberrations of the eye, or predefined two-dimensional icons that provide a general graphical depiction of such pre-specified terms. Such graphical representations provide the practitioner with valuable information characterizing the high order optical errors of the eye for use in diagnosis and treatment of abnormalities and disease in the eye. In addition, the wavefront sensor may be part of an adaptive optical subsystem that compensates for the phase aberrations measured therein to provide phase-aligned images of the eye for capture by an image capture subsystem. Such images may be used by practitioner in diagnosis and treatment of abnormalities and disease in the eye.

Method of treating the human eye with a wavefront sensor-based ophthalmic instrument

The present invention relates to methods of implementing an optical element having a refraction modulating composition. The methods include using a wavefront sensor to provide an optical measurement of the optical element. The present invention also relates to systems comprising an optical element having a refraction modulating composition and a wavefront sensor. An embodiment is described in which the optical element is an intraocular lens. Optical aberrations of the lens measured by the wavefront sensor are corrected by photo-polymerization of the refraction modulating composition which alters the refractive properties of the lens. Correction of lens refractive errors can be carried out after the lens has been implanted in the eye.

Application of wavefront sensor to lenses capable of post-fabrication power modification

The disclosure concerns altering the mechanical and/or chemical property of a body tissue, particularly an ocular tissue. In specific cases, it concerns altering or stabilizing the shape of the cornea, such as in a subject suffering or at risk for ectasia or keratoconus. In other specific cases, it concerns strengthening the sclera in a subject suffering or at risk for myopia. The invention employs light irradiation of a photoactivatable compound, such as one that applies crosslinking to the tissue, for example.

Photochemical therapy to affect mechanical and/or chemical properties of body tissue

A method for evaluating the effectiveness of adjustable optical implants is provided The implants are first inserted into a test subject. The implant is then exposed to an external stimulus, such as light, to induce a change in the properties of the implant. The implants are then evaluated to determine the nature and extent of the change in properties.

Intraoccular lenses capable of in vivo power adjustment and method for same

L'invention concerne une modification de la propriete mecanique et/ou chimique d'un tissu cellulaire, en particulier d'un tissu oculaire. Dans des cas precis, l'invention concerne une modification ou une stabilisation de la forme de la cornee, telle que chez un sujet souffrant d'ectasie ou de keratocone ou presentant un risque d'ectasie ou de keratoncone. Dans d'autres cas particuliers, l'invention concerne un renforcement de la sclerotique chez un sujet souffrant de myopie ou presentant un risque de myopie. L'invention utilise un rayonnement de lumiere d'un compose pouvant etre photo-active, tel qu'il peut appliquer une reticulation au tissu, par exemple.

Thérapie photochimique pour avoir une incidence des propriétés mécaniques et/ou chimiques du tissu cellulaire

A method for evaluating the effectiveness of adjustable optical implants is provided. The implants are first inserted into a test subject. The implant is then exposed to an external stimulus, such as light, to induce a change in the properties of the implant. The implants are then evaluated to determine the nature and extent of the change in properties.

Intraoccular lenses with power adjustability in vivo

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