Robert L. Taylor
Children's Memorial Hospital
4 Papers
6 Citations
Robert L. Taylor is an academic researcher from Children's Memorial Hospital. The author has contributed to research in topics: Oncofertility & Transcription factor. The author has an hindex of 2, co-authored 4 publications. Previous affiliations of Robert L. Taylor include Northwestern University.
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Papers
CRISPR editing of the GLI1 first intron abrogates GLI1 expression and differentially alters lineage commitment.
Yekaterina Galat,Yekaterina Galat,Yekaterina Galat,Haigang Gu,Mariana Perepitchka,Mariana Perepitchka,Robert L. Taylor,Joon Won Yoon,Xenia A. Glukhova,Xiao-Nan Li,Igor P. Beletsky,David O. Walterhouse,David O. Walterhouse,Vasiliy Galat,Philip M. Iannaccone +14 more
TL;DR: The role of GLI1 and its intronic regulatory locus on human stem cell differentiation was investigated in this article, where the authors found a delay in the onset of early osteogenic markers, a reduction in the hematopoietic potential to form granulocyte units, and a decrease in cancer-related gene expression.
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Understanding Technology and Human Interaction to Catalyze Oncofertility and Adolescent and Young Adult Oncology Research.
TL;DR: The adolescent and young adult oncology population, defined by the National Cancer Institute as those aged 15–39 at the time of cancer diagnosis, poses a unique set of challenges to the medical community, so it is imperative to understand how cancer impedes the normal developmental process and to cultivate a healthcare community that responds to this distinctive subset of cancer patients synergistically.
Future Directions in Oncofertility and Fertility Preservation: A Report from the 2011 Oncofertility Consortium Conference
Kate E. Waimey,Francesca E. Duncan,H. Irene Su,Kristin Smith,Harlan Wallach,Kemi Jona,Christos Coutifaris,Clarisa R. Gracia,Lonnie D. Shea,Robert E. Brannigan,R. Jeffrey Chang,Mary B. Zelinski,Richard L. Stouffer,Robert L. Taylor +13 more
TL;DR: This summary from conference participants and leaders in the field addresses the science, clinical specialties, and academic scholarship that can guide the field as the Roadmap Grant funding comes to a close.
Regulation of GLI1 by cis DNA elements and epigenetic marks.
Robert L. Taylor,Jun Long,Joon Won Yoon,Ronnie Childs,Kathrine B. Sylvestersen,Michael L. Nielsen,King Fu Leong,Stephen Iannaccone,David O. Walterhouse,David J. Robbins,Philip M. Iannaccone +10 more
TL;DR: The results suggest that GLI1 and GLI2 can regulateGLI1 expression through protein-protein interactions involving complexes of transcription factors, histone variants, and reader proteins in the regulatory intron of the GLI 1 gene.