Robert Hett
University of Regensburg
5 Papers
43 Citations
Robert Hett is an academic researcher from University of Regensburg. The author has contributed to research in topics: Biology & Translation (biology). The author has an hindex of 5, co-authored 5 publications.
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Papers
Silacidins: Highly Acidic Phosphopeptides from Diatom Shells Assist in Silica Precipitation In Vitro
TL;DR: A new class of aspartate/glutamate-rich and serine phosphate rich peptides as constituents of biosilica produced by the diatom Thalassiosira pseudonana is described, known as silacidins due to their presence in silica and their acidic nature.
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Comprehensive analysis of translation from overexpressed circular RNAs reveals pervasive translation from linear transcripts.
Hung Ho-Xuan,Petar Glažar,Claudia Latini,Kevin Heizler,Jacob Haase,Robert Hett,Marvin Anders,Franziska Weichmann,Astrid Bruckmann,Debbie L. C. van den Berg,Stefan Hüttelmaier,Nikolaus Rajewsky,Christina Hackl,Gunter Meister +13 more
TL;DR: It is reported that the ORF of circZNF609 is efficiently translated when expressed from a circZ NF609 overexpression construct, however, endogenous proteins could not be detected and underline that circRNA overexposure constructs need to be evaluated carefully, particularly when functional studies are performed.
Validation strategies for antibodies targeting modified ribonucleotides.
Franziska Weichmann,Robert Hett,Aloys Schepers,Taku Ito-Kureha,Andrew Flatley,Kaouthar Slama,Florian D. Hastert,Nicholas B. Angstman,M. Cristina Cardoso,Julian König,Stefan Hüttelmaier,Christoph Dieterich,Stefan Canzar,Mark Helm,Vigo Heissmeyer,Regina Feederle,Gunter Meister +16 more
TL;DR: Here, a experimental toolbox is provided that allow for testing antibody performance prior to their use before they are used and is critical that the affinity and specificity is rigorously tested using complementary approaches.
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