Robert G. Schaub
Pfizer
97 Papers
1.1K Citations
Robert G. Schaub is an academic researcher from Pfizer. The author has contributed to research in topics: Von Willebrand factor & Thrombosis. The author has an hindex of 38, co-authored 96 publications. Previous affiliations of Robert G. Schaub include Genetics Institute, Inc. & Baxter International.
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Papers
Resolution of cutaneous leishmaniasis: interleukin 12 initiates a protective T helper type 1 immune response.
Joseph P. Sypek,Charles L. Chung,Sharon E. H. Mayor,Janaki M. Subramanyam,Samuel J. Goldman,Derek Sieburth,Stanley F. Wolf,Robert G. Schaub +7 more
TL;DR: It is suggested that IL-12 has an important role in initiating a Th1 response and protective immunity in resistant mice, as seen in the case of highly susceptible BALB/c mice.
773
First-in-Human Evaluation of Anti–von Willebrand Factor Therapeutic Aptamer ARC1779 in Healthy Volunteers
James C. Gilbert,Tia DeFeo-Fraulini,Renta Hutabarat,Christopher J. Horvath,Patricia G. Merlino,H. Nicholas Marsh,Judith M. Healy,Sleiman BouFakhreddine,Thomas V. Holohan,Robert G. Schaub +9 more
TL;DR: ARC1779 produced dose- and concentration-dependent inhibition of vWF activity and platelet function with duration of effect suitable for the intended clinical use in acute coronary syndromes, and was generally well tolerated.
290
P-selectin and leukocyte microparticles are associated with venous thrombogenesis
Daniel D. Myers,Angela E. Hawley,Diana M. Farris,Shirley K. Wrobleski,Porama Thanaporn,Robert G. Schaub,Denisa D. Wagner,Anjali Kumar,Thomas W. Wakefield +8 more
TL;DR: It is demonstrated that high circulating levels of P-selectin are associated with increased thrombosis, whereas a lack of P -selectin and E- selectin is associated with a lessening of thromBosis, and leukocyte MPs areassociated with venous thrombus formation.
245
DANCE, a Novel Secreted RGD Protein Expressed in Developing, Atherosclerotic, and Balloon-injured Arteries
Tomoyuki Nakamura,Pilar Ruiz-Lozano,Volkhard Lindner,Daisuke Yabe,Masafumi Taniwaki,Yutaka Furukawa,Kazuhiro Kobuke,Kei Tashiro,Zhijian Lu,Nancy L. Andon,Robert G. Schaub,Akira Matsumori,Shigetake Sasayama,Kenneth R. Chien,Tasuku Honjo +14 more
TL;DR: DANCE protein was shown to promote adhesion of endothelial cells through interaction of integrins and the RGD motif of DANCE, thus DANCE is thus a novel vascular ligand for integrin receptors and may play a role in vascular development and remodeling.
191
Healing of large segmental defects in rat femurs is aided by RhBMP-2 in PLGA matrix.
S. C. Lee,M. Shea,M. A. Battle,K. Kozitza,Eyal S. Ron,Tom Turek,Robert G. Schaub,Wilson C. Hayes +7 more
TL;DR: In this article, the effects of a fibrinolytic inhibitory agent, epsilon aminocaproic acid (EACA), on the healing response of rat femurs were investigated.
184