Drug releasing anastomosis devices and methods for treating anastomotic sites

A multiple-sided medical device (10) comprises a frame (11) comprising wire or other resilient material and having a series of bends (12) and interconnecting sides. The device is pushed from a delivery catheter into the lumen of a duct or vessel and may include one or more barbs (16) for anchoring purposes. A full or partial covering (45) of fabric or other flexible material such as DACRON, PTFE, or a collagen-based material such as small intestinal submucosa (SIS), may be sutured or attached to the frame to form an occlusion device (51), a stent graft (75), or an implantable, intraluminal valve (43) such as for correcting incompetent veins in the lower legs and feet.

Implantable vascular device

The present invention concerns novel stent apparatuses for use in treating lesions at or near the bifurcation point in bifurcated cardiac, coronary, renal, peripheral vascular, gastrointestinal, pulmonary, urinary and neurovascular vessels and brain vessels More particularly, the invention concerns a stent apparatus with at least one side opening which may further comprise an extendable stent portion laterally extending from the side opening and at least partly in registry with the wall of the side opening Devices constructed in accordance with the invention include, singularly or in combination, a main expandable stent comprising at least one substantially circular side opening located between its proximal and distal end openings, which side opening may further comprise an expandable portion extending radially outward from the edges of the side opening; and a branch stent comprising proximal and distal end openings and which may further comprise a contacting portion at its proximal end, and which may optionally be constructed to form either a perpendicular branch or a non-perpendicular branch when inserted through a side opening of the main stent The stents of the invention are marked with, or at least partially constructed of, a material which is imageable during intraluminal catheterization techniques, most preferably but not limited to ultrasound and x-ray

Extendible Stent Apparatus

An expandable venous valve having a support structure (11) that configured to enlarge the area adjacent to the valve structure (12) such that the flow patterns of retrograde flow are modified in a way that facilitates the flushing of the pockets at the base of the valve area to prevent stagnation of bodily fluid, which in the venous system, can lead to thrombus formation. The enlarged pocket areas can be created by forming an artificial sinus (34) adjacent the valve structure in an unsupported section of vessel wall between two support frame section or the support frame can comprise an expanded-diameter intermediate or proximal section that forms an artificial sinus adjacent the valve structure. In another group of embodiments, the attachment pathway between opposing leaflets and the support frame and/or vessel wall comprises a proximal portion that places the leaflets in extended contact with one another and a distal portion forms a large angle with respect to the adjacent walls such that a large pocket is created at the base of the leaflets. In one embodiment, the attachment pathway extends distally along a pair of substantially parallel longitudinal attachment struts to create an extended leaflet contact area, then angles circumferentially and distally from the former along distal attachment struts to define the bottom edge of the leaflets.

Artificial valve prosthesis with improved flow dynamics

A multiple-sided medical device comprises a closed frame of a single piece of wire or other resilient material and having a series of bends and interconnecting sides. The device has both a flat configuration and a second, folded configuration that comprises a self-expanding stent. The stent is pushed from a delivery catheter into the lumen of a duct or vessel. One or more barbs are attached to the frame of the device for anchoring or to connect additional frames. A covering of fabric or other flexible material such as DACRON, PTFE, or collagen, is sutured or attached to the frame to form an occlusion device, a stent graft, or an artificial valve such as for correcting incompetent veins in the lower legs and feet. A partial, triangular-shaped covering over the lumen of the device allows the valve to open with normal blood flow and close to retrograde flow.

Multiple-sided intraluminal medical device

A stent in the form of a thin-walled, multi-cellular tubular structure is provided. The tubular structure has a longitudinal axis and the stent includes a plurality of circumferential sets of strut members. Each set of the strut members is longitudinally displaced from each other and connected to each other by longitudinally extending links. Each set of the strut members forms a closed and cylindrical portion of the stent. Further, each set of the strut members includes a plurality of connected curve sections and diagonal sections. The sets of the strut members further include end sets of strut members located at each end of the stent and central sets of strut members located between the end sets of the strut members. The diagonal sections of the end sets of the strut members have a center portion and two ends. At least one of the diagonal sections of the end sets of the strut members includes a tapered shape with width of one diagonal section is greater at the center of the diagonal section than the width at either end of the diagonal section.

Stent with optimal strength and radiopacity characteristics

The present invention provides for an expandable stent (1) for use in an artery or other vessel of a human body which forms a plurality of spaced apart generally circular rings (2). The stent structure (1) maintains patency of a vessel within which the stent (1) is inserted and is formed by a plurality of closed and generally circular rings (2) where the plane of each ring (2) is substantially parallel to the plane of an adjacent ring (2). The rings (2) have a common longitudinal axis generally perpendicular to the plane of each ring (2) with the longitudinal axis passing through the geometric center of each of the rings (2). A plurality of elongated wire structures forming longitudinals (4T, 4B, 4R, 4L) are fixedly secured to the rings (2) and extend in a direction generally parallel to the longitudinal axis of the rings (2). The stent (1) formed of the generally circular rings (2) optimizes hoop strength and minimizes elastic recoil of a vessel into which the stent (1) is inserted.

Stent having a multiplicity of closed circular structures

Disclosed is a comparatively thick-walled vascular stent comprising sets of strut members connected by flexible, longitudinally extending links This design utilizes flexible links with a variety of different shapes Adjacent flexible links around the circumference of the stent are designed to nest one into the other, allowing the stent to be both thick-walled and to crimp down without overlap onto a low profile balloon The flexible links are attached to the sets of strut members not at the center like the “S” links of prior art stents, but off center near the end of the curved strut portion of each set of strut members This off center attachment point allows for a more flexible link without increasing the cell size of the expanded stent Small cell size is desirable to limit plaque prolapse into the lumen of the expanded stent and to increase the stent's radial rigidity The relatively thin strut width with thick wall allows the flexible links to easily lengthen and shorten during stent delivery into the body while still providing each flexible link with a considerable degree of radial strength

Low profile radiopaque stent with increased longitudinal flexibility and radial rigidity

The present invention is a stent delivery system that uses a short section of a guide wire that is fixedly attached to a distal section of a balloon angioplasty catheter. By not having a guide wire that slides through the balloon of the balloon angioplasty catheter, the balloon on which the stent is mounted can have a reduced diameter. Therefore, the outside diameter of the undeployed stent mounted onto that balloon is also minimized. This provides a minimum profile, i.e., a minimum outside diameter, for the stent. A minimum profile at the distal section of the stent delivery system is highly advantageous for improving the percentage of cases that can be treated by means of direct stenting; i.e., without requiring pre-dilation of a stenosis.

Stent delivery system with a fixed guide wire

Disclosed is a stent that has flexible connecting links that have a strut width as measured in a direction that is generally along the surface of the stent that is smaller than the wall thickness of the stent as measured in a radial direction from the stent's longitudinal axis. The strut width for a coronary stent should be less than 0.10 mm to provide good flexibility while the wall thickness should be greater than 0.10 mm to provide good stent radiopacity. Ideally the ratio of the width to the thickness should be less than 1.0 and preferably less than 0.08 mm and the nominal wall thickness would typically be 0.12 mm. The combination of thin strut width and thick wall thickness will allow the flexible link to easily lengthen and shorten for increased stent flexibility while making the link relatively stiff with respect to bulging inward into the lumen of the stent. This stiffness enhances the ability of the link to push outward against plaque in a coronary artery after the stent is deployed. In addition to improved flexibility, the thin width of the flexible links allow them to stretch during stent expansion thus reducing foreshortening of the deployed stent.

Stent with improved flexible connecting links

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