https://jada.ada.org/article/S0002-8177(64)86004-9/pdf

Staining test for delineation of oral intraepithelial neoplasms

Oral exfoliative study. Review of the literature and report of a three-year study.

Quantitative cytophotometric analysis may be a useful adjunct to the detection of recurrence of malignancy, prior to it becoming visible, clinically. A case is reported by which DNA cytophotometry indicated recurrence on two occasions prior to its clinical diagnosis.

Quantitative cytophotometric analysis as an aid to the detection of recurrent oral cancer.

IN RECENT years there have been far too many casual and unsupported statements concerning the reliability of biopsies and cytologic smears in the diagnosis of oral cancer and other oral lesions. There are, to date, surprisingly few carefully controlled studies in which significant numbers of oral lesions have been subjected to both cytodiagnostic and histopathologic evaluation and study in each instance. 1,2 Many studies in oral cytology have presented data that are not well substantiated, since biopsies were not obtained in all cases. 3,4 The problems of this type of study have been discussed. 5,6 False positive results in cytologic evaluation present no significant problem, since immediate follow-up and biopsy is mandatory in order to confirm the diagnosis of carcinoma. False negative results in cytologic evaluation present a real hazard in cancer management, since biopsy will often not be done until such time as the clinical features of a proliferating

Reliability of Cytologic Smear in Diagnosis of Oral Cancer: A Controlled Study

To assess the value of the negative cytologic diagnosis, findings from histologic and cytologic specimens from suspicious and innocuous-appearing lesions of the lips and oral cavity were correlated. About 26 percent of the instances of histologically proved cancer were negative cytologically.

https://jada.ada.org/article/S0002-8177(67)43029-3/pdf

An assessment of the negative oral cytologic diagnosis.

https://acsjournals.onlinelibrary.wiley.com/doi/epdf/10.1002/1097-0142%28196302%2916%3A2%3C160%3A%3AAID-CNCR2820160203%3E3.0.CO%3B2-3

Exfoliative cytology and the early diagnosis of oral cancer.

ESPITE THE ACCESSIBILITY OF THE ORAL CAVD ity to examination it is discouraging to be confronted with the degree of advanced neoplastic disease that patients present. Symptoms are invariably associated with lesions that do not present diagnostic difficulties, but rather jx-oblems in management and treatment. The problcm of early diagnasis necessitated realization that the patient with early cancer would present no symptoms, and that we had no clear idea as to what early cancer would look like. T o this end, careful examination of tlic oral cavity was performed by members of our dental and tumor services, and this was 5iipplemcnted by the use of exfoliative cytology and biopsies. We had little doubt that properly collected smears of oral lcsions would in most cases yield material of diagnostic value. During the past 4 yews exfoliative cytoIOgici11 studies haw been applied as an adjunct to the diagnosis of carcinoma of the oral cavity. Published reports on the use of exfoliative q-

Exfoliative cytology and the early diagnosis of oral cancer

Palatal aneurysm; review of the literature and report of a case.

Some observations on carcinoma of the lip.

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Exfoliative cytology and the early diagnosis of oral cancer.

Exfoliative cytology and the early diagnosis of oral cancer

Palatal aneurysm; review of the literature and report of a case.

Some observations on carcinoma of the lip.