Robert A. Koeppe
University of Michigan
445 Papers
3.9K Citations
Robert A. Koeppe is an academic researcher from University of Michigan. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 102, co-authored 389 publications. Previous affiliations of Robert A. Koeppe include University of Pittsburgh & University of Washington.
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Papers
Deep learning-based polygenic risk analysis for Alzheimer’s disease prediction
Xiaopu Zhou,Yu Chen,Fanny C.F. Ip,Yuanbing Jiang,Han Cao,Gengsi Lv,Huan-Qiong Zhong,Jiahang Chen,Tao Ye,Yuewen Chen,Yulin Zhang,Shuangshuang Ma,Ronnie M. N. Lo,Estella P.S. Tong,Michael W. Weiner,P. Aisen,Ronald C. Petersen,Clifford R. Jack,William J. Jagust,John Q. Trojanowski,Arthur W. Toga,Laurel A. Beckett,Robert C Green,Andrew J. Saykin,J.H. Morris,Leslie M. Shaw,Zaven S. Khachaturian,Greg Sorensen,Lew Kuller,Marcus E. Raichle,Steven M. Paul,Peter Davies,Howard Fillit,Franz Hefti,David M. Holtzman,M. Marcel Mesulam,William Z. Potter,Peter J. Snyder,Adam Schwartz,Thomas J. Montine,Ronald G. Thomas,Michael C. Donohue,Sarah Walter,Devon Gessert,Tamie Sather,Gus Jiminez,Danielle J Harvey,M S Bernstein,Paul M. Thompson,Norbert Schuff,Bret J. Borowski,Jeff Gunter,Matthew L. Senjem,Prashanthi Vemuri,David T.W. Jones,Kejal Kantarci,Chadwick P. Ward,Robert A. Koeppe,Norman L. Foster,Eric M. Reiman,Kewei Chen,Chet Mathis,Susan M. Landau,Nigel J. Cairns,Erin Householder,Lisa Taylor-Reinwald,Virginia M.-Y. Lee,Magdalena Korecka,Michal J. Figurski,Karen Crawford,Scott C. Neu,Tatiana Foroud,Steven G. Potkin,Li Shen,Kelley Faber,Sungeun Kim,Kwangsik Nho,L. Thal,Neil Buckholtz,M.S. Albert,Richard Frank,John K. Hsiao,Jeffrey Kaye,Joseph F. Quinn,Betty Lind,Raina Carter,Sara Dolen,Lon S. Schneider,Sonia Pawluczyk,Mauricio Beccera,Liberty Teodoro,Bryan M. Spann,James B. Brewer,Helen Vanderswag,Adam S. Fleisher,Judith L. Heidebrink,Joanne L. Lord,Sara S. Mason,Colleen S. Albers,David S. Knopman,Chris A. Johnson,Rachelle S. Doody,Javier Villanueva-Meyer,Munir Chowdhury,Susan Rountree,Mimi Dang,Yaakov Stern,Lawrence S. Honig,Karen L. Bell,Beau M. Ances,Maria Carroll,Sue Leon,Mark A. Mintun,Stacy Schneider,Angela Oliver,D G Marson,Randall Griffith,David Clark,David S. Geldmacher,John C. Brockington,Erik D. Roberson,Hillel Grossman,Effie M. Mitsis,Leyla de Toledo-Morrell,Raj C. Shah,Ranjan Duara,Daniel Varon,Maria T. Greig,Peggy Roberts,Chiadi U. Onyike,Daniel D'Agostino,Stephanie Kielb,James E. Galvin,Brittany Cerbone,Christina A. Michel,Henry Rusinek,Mony J. de Leon,Lidia Glodzik,Susan De Santi,P. Murali Doraiswamy,Jeffrey R. Petrella,Terence Z. Wong,Steven E. Arnold,Jason Karlawish,David A. Wolk,Charles D. Smith,G. Jicha,Peter Hardy,Partha Sinha,Elizabeth Oates,Gary R. Conrad,Oscar L. Lopez,MaryAnn Oakley,Donna M. Simpson,Anton P. Porsteinsson,Bonnie S. Goldstein,Kim Martin,Kelly M. Makino,M. Saleem Ismail,Connie Brand,Ruth A. Mulnard,Gaby Thai,Catherine McAdams-Ortiz,Kyle B. Womack,Dana Mathews,Mary Quiceno,Ramon F. Diaz-Arrastia,Richard D. King,M. Weiner,Kristen Martin-Cook,Michael D. Devous,Allan I. Levey,James J. Lah,Janet S. Cellar,Jeffrey M. Burns,Heather Anderson,Russell H. Swerdlow,Liana G. Apostolova,Kathleen Tingus,Ellen Woo,Daniel H.S. Silverman,Po H. Lu,George Bartzokis,Neill R. Graff-Radford,Francine Parfitt,Tracy Kendall,Heather E. Johnson,Martin R. Farlow,Ann Marie Hake,Brandy R. Matthews,Scott Herring,Cynthia Louise Lytle Hunt,Christopher H. van Dyck,Richard E. Carson,Martha G. MacAvoy,Howard Chertkow,Howard Bergman,Chris Hosein,Ging-Yuek Robin Hsiung,Howard Feldman,Benita Mudge,Michele Assaly,Charles Bernick,Donna Munic,Andrew Kertesz,John Rogers,Dick Trost,Diana R. Kerwin,Kristine Lipowski,Chuang Kuo Wu,Nancy Johnson,Carl H. Sadowsky,Walter Martinez,Teresa Villena,R. Scott Turner,Kathleen R. Johnson,Brigid Reynolds,Reisa A. Sperling,Keith A. Johnson,Gad A. Marshall,Meghan Frey,Barton Lane,Allyson C. Rosen,Jared R. Tinklenberg,Marwan N. Sabbagh,Christine Belden,Sandra W. Jacobson,Sherye A. Sirrel,Neil W. Kowall,Ronald J. Killiany,Andrew E. Budson,Alexander Norbash,Patricia Lynn Johnson,Joanne S. Allard,Alan J. Lerner,Paula Ogrocki,Leon Hudson,Evan Fletcher,Owen Carmichael,John M Olichney,Charles DeCarli,Smita Kittur,Michael Borrie,T. Lee,Robert Bartha,Sterling Johnson,Sanjay Asthana,Cynthia M. Carlsson,Adrian Preda,Dana Nguyen,Pierre N. Tariot,Stephanie Reeder,Vernice Bates,Horacio Capote,Michelle Rainka,Douglas W. Scharre,Maria Kataki,Anahita Adeli,Earl A. Zimmerman,Dzintra Celmins,Alice D. Brown,Godfrey D. Pearlson,Karen Blank,Karen E. Anderson,Robert B. Santulli,Tamar J. Kitzmiller,Eben S. Schwartz,Kaycee M. Sink,Jeff D. Williamson,Pradeep Garg,Franklin Watkins,Brian R. Ott,Henry W. Querfurth,Geoffrey Tremont,Stephen Salloway,Paul Malloy,Stephen Correia,Howard J. Rosen,Bruce L. Miller,Jacobo Mintzer,Kenneth M. Spicer,David Bachman,Stephen H. Pasternak,Irina Rachinsky,Dirk C. Drost,Nunzio Pomara,Raymundo Hernando,Antero Sarrael,Susan K. Schultz,Laura L. Boles Ponto,Hyungsub Shim,Karen E. Smith,Norman R. Relkin,Gloria Chaing,Lisa Raudin,Amanda Smith,Kristin Fargher,Balebail Ashok Raj,Thomas C. Neylan,Jordan Grafman,Melissa Davis,Rosemary H Morrison,Jacqueline Hayes,Shannon Rose Finley,K. J. Friedl,Debra A. Fleischman,Konstantinos Arfanakis,Olga James,Dino Massoglia,J. Jay Fruehling,Sandra Harding,Elaine R. Peskind,Eric C. Petrie,Gail Li,Jerome A. Yesavage,Joy L. Taylor,Ansgar J. Furst,Vincent Mok,Timothy Kwok,Qihao Guo,Kin Y. Mok,Maryam Shoai,John Hardy,Lei Chen,Amy K.Y. Fu,Nancy Y. Ip +325 more
TL;DR: In this article , a deep learning neural network model was proposed to predict polygenic risk of Alzheimer's disease. But, the model was not able to capture the complexity of genomic data, and current statistical analyses cannot comprehensively capture the polygenic risk of AD, resulting in unsatisfactory disease risk prediction.
Dissociation of tau pathology and neuronal hypometabolism within the ATN framework of Alzheimer’s disease
Michael Tran Duong,Sandhitsu R. Das,Xueying Lu,Long Xie,Hayley Richardson,Sharon X. Xie,Paul A. Yushkevich,Michael W. Weiner,P. Aisen,Ronald C. Petersen,Clifford R. Jack,William J. Jagust,John Q. Trojanowki,Arthur W. Toga,Laurel A. Beckett,Robert C. Green,Andrew J. Saykin,John C. Morris,Leslie M. Shaw,Enchi Liu,Thomas J. Montine,Ronald G. Thomas,Michael C. Donohue,Sarah Walter,Devon Gessert,Tamie Sather,Gustavo Jimenez-Maggiora,Danielle J Harvey,M S Bernstein,Nick C. Fox,Paul M. Thompson,Norbert Schuff,Charles DeCarli,Bret J. Borowski,Jeff Gunter,Matthew L. Senjem,Prashanthi Vemuri,David T.W. Jones,Kejal Kantarci,Chadwick P. Ward,Robert A. Koeppe,Norman L. Foster,Eric M. Reiman,Kewei Chen,Chet Mathis,Susan M. Landau,Nigel J. Cairns,Erin Householder,Lisa Taylor-Reinwald,Virginia M.-Y. Lee,Magdalena Korecka,Michal J. Figurski,Karen Crawford,Scott C. Neu,Tatiana Foroud,Li Shen,Kelley Faber,Sungeun Kim,Kwangsik Nho,Zaven S. Khachaturian,Richard Frank,Peter J. Snyder,Susan E. Molchan,Jeffrey Kaye,Joseph F. Quinn,Betty Lind,Raina Carter,Sara Dolen,Lon S. Schneider,Sonia Pawluczyk,Mauricio Beccera,Liberty Teodoro,Bryan M. Spann,James B. Brewer,Helen Vanderswag,Adam S. Fleisher,Judith L. Heidebrink,Joanne L. Lord,Sara S. Mason,Colleen S. Albers,David S. Knopman,Chris A. Johnson,Rachelle S. Doody,Javier Villanueva-Meyer,Munir Chowdhury,Susan Rountree,Mimi Dang,Yaakov Stern,Lawrence S. Honig,Karen L. Bell,Beau M. Ances,Maria Carroll,Sue Leon,Mark A. Mintun,Stacy Schneider,Angela Oliver,Randall Griffith,David Clark,David S. Geldmacher,John C. Brockington,Erik D. Roberson,Hillel Grossman,Effie M. Mitsis,Leyla Detoledo-Morrell,Raj C. Shah,Ranjan Duara,Daniel Varon,Maria T. Greig,Peggy Roberts,Marilyn S. Albert,Chiadi U. Onyike,Daniel D'Agostino,Stephanie Kielb,James E. Galvin,D. Pogorelec,Brittany Cerbone,Christina A. Michel,Henry Rusinek,Mony J. de Leon,Lidia Glodzik,Susan De Santi,P. Murali Doraiswamy,Jeffrey R. Petrella,Terence Z. Wong,Christopher M. Clark,Steven E. Arnold,Jason Karlawish,Charles D. Smith,Gregory A. Jicha,Peter Hardy,Partha Sinha,Elizabeth Oates,Gary R. Conrad,Oscar L. Lopez,MaryAnn Oakley,Donna M. Simpson,Anton P. Porsteinsson,Bonnie S. Goldstein,Kim Martin,Kelly M. Makino,M. Saleem Ismail,Connie Brand,Ruth A. Mulnard,Gaby Thai,Catherine McAdams-Ortiz,Kyle B. Womack,Dana Mathews,Mary Quiceno,Ramon F. Diaz-Arrastia,Richard D. King,M. Weiner,Kristen M. Cook,Michael D. Devous,Allan I. Levey,James J. Lah,Janet S. Cellar,Jeffrey M. Burns,Heather Anderson,Russell H. Swerdlow,Liana G. Apostolova,Kathleen Tingus,Ellen Woo,Daniel H.S. Silverman,Po H. Lu,George Bartzokis,Neill R. Graff-Radford,Francine Parfitt,Tracy Kendall,Heather E. Johnson,Martin R. Farlow,Ann Marie Hake,Brandy R. Matthews,Scott Herring,Cynthia Louise Lytle Hunt,Christopher H. van Dyck,Richard E. Carson,Martha G. MacAvoy,Howard Chertkow,Howard Bergman,Chris Hosein,Sandra E. Black,Bojana Stefanovic,Curtis B. Caldwell,Ging-Yuek Robin Hsiung,Howard Feldman,Benita Mudge,Michele Assaly,Andrew Kertesz,John Rogers,Charles Bernick,Donna Munic,Diana R. Kerwin,M.-Marsel Mesulam,Kristine Lipowski,Chuang Kuo Wu,Nancy Johnson,Carl H. Sadowsky,Walter Martinez,Teresa Villena,R. Scott Turner,Kathleen R. Johnson,Brigid Reynolds,Reisa A. Sperling,Keith A. Johnson,Gad A. Marshall,Meghan Frey,Jerome A. Yesavage,Joy L. Taylor,Barton Lane,Allyson C. Rosen,Jared R. Tinklenberg,Marwan N. Sabbagh,Christine Belden,Sandra W. Jacobson,Sherye A. Sirrel,Neil W. Kowall,Ronald J. Killiany,Andrew E. Budson,Alexander Norbash,Patricia Lynn Johnson,Thomas O. Obisesan,Saba Wolday,Joanne S. Allard,Alan J. Lerner,Paula Ogrocki,Leon Hudson,Evan Fletcher,Owen Carmichael,John M Olichney,Smita Kittur,Michael Borrie,T. Lee,Robert Bartha,Sterling C. Johnson,Sanjay Asthana,Cynthia M. Carlsson,Steven G. Potkin,Adrian Preda,Dana Nguyen,Pierre N. Tariot,Stephanie A. Reeder,Vernice Bates,Horacio Capote,Michelle Rainka,Douglas W. Scharre,Maria Kataki,Anahita Adeli,Earl A. Zimmerman,Dzintra Celmins,Alice D. Brown,Godfrey D. Pearlson,Karen Blank,Karen E. Anderson,Robert B. Santulli,Tamar J. Kitzmiller,Eben S. Schwartz,Kaycee M. Sink,Jeff D. Williamson,Pradeep Garg,Franklin Watkins,Brian R. Ott,Henry W. Querfurth,Geoffrey Tremont,Stephen Salloway,Paul Malloy,Stephen Correia,Howard J. Rosen,Bruce L. Miller,Jacobo Mintzer,Kenneth M. Spicer,David Bachman,Elizabeth Finger,Stephen H. Pasternak,Irina Rachinsky,Dirk C. Drost,Nunzio Pomara,Raymundo Hernando,Antero Sarrael,Susan K. Schultz,Laura L. Boles Ponto,Hyungsub Shim,Karen E. Smith,Norman R. Relkin,Gloria C. Chiang,Lisa D. Ravdin,Amanda Smith,Kristin Fargher,Balebail Ashok Raj,David A. Wolk,Ilya M. Nasrallah +289 more
TL;DR: In this paper , the authors assessed heterogeneity in 18F-flortaucipir vs. 18Ffluorodeoxyglucose positron emission tomography as markers of T and neuronal hypometabolism (NM) in 289 symptomatic patients from the Alzheimer's Disease Neuroimaging Initiative.
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Prevalence of impaired odor identification in Parkinson disease with imaging evidence of nigrostriatal denervation.
Jacob Haugen,Martijn L.T.M. Müller,Vikas Kotagal,Roger L. Albin,Robert A. Koeppe,Peter J. H. Scott,Kirk A. Frey,Nicolaas I. Bohnen +7 more
TL;DR: This study assessed the prevalence of abnormal smell, using the University of Pennsylvania Smell Identification Test (UPSIT), in 183 patients with PD with confirmed PET imaging evidence of nigrostriatal denervation, andpaired olfaction in this sample was nearly universal.
Denicotinized versus average nicotine tobacco cigarette smoking differentially releases striatal dopamine
Edward F. Domino,Lisong Ni,Lisong Ni,Joseph S. Domino,Wendy Yang,Catherine L. Evans,Sally K. Guthrie,Heng Wang,Robert A. Koeppe,Jon Kar Zubieta,Jon Kar Zubieta +10 more
TL;DR: Nonnicotine factors in tobacco smoking produce important right brain effects that releases bilateral striatal DA, but more in the left brain than in the right brain during tobacco smoking.
PET Study of Greater Visual Activation in Schizophrenia
TL;DR: The authors tested the hypothesis that photic visual stimuli cause a greater blood flow activation response in subjects with schizophrenia than in normal subjects to investigate the mechanisms of activation during sensory stimulation in schizophrenia.
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