Robert A. Heinzen
Washington State University
10 Papers
115 Citations
Robert A. Heinzen is an academic researcher from Washington State University. The author has contributed to research in topics: Coxiella burnetii & Open reading frame. The author has an hindex of 8, co-authored 10 publications. Previous affiliations of Robert A. Heinzen include Battelle Memorial Institute.
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Papers
Strategy for detection and differentiation of Coxiella burnetii strains using the polymerase chain reaction.
Louis P. Mallavia,L. L. Whiting,Michael F. Minnick,Robert A. Heinzen,Robert A. Heinzen,M. Foreman,Oswald G. Baca,M. E. Frazier +7 more
TL;DR: A method for the rapid detection of Coxiella burnetii and differentiation between strains that cause endocarditis and those that cause acute Q fever is based on the observation that the different strains contain unique plasmid sequences.
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Characterization and expression of the cbbE' gene of Coxiella burnetii.
TL;DR: A gene which is unique to the QpRS plasmid from chronic isolates of Coxiella burnetii was cloned, sequenced, and expressed in Escherichia coli, yielding a novel protein that can be detected on immunoblots developed with rabbit antiserum generated against purified outer membrane from C. burnsetii.
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A plasmid-encoded surface protein found in chronic-disease isolates of Coxiella burnetti.
TL;DR: The predicted hydropathy profile of E' is similar to profiles of known outer membrane proteins and corroborates the biochemical data, indicating that the protein is located in the outer membrane of C. burnetii.
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Characterization of the succinate dehydrogenase-encoding gene cluster (sdh) from the rickettsia Coxiella burnetii.
TL;DR: Evidence that sucA transcription can occur independent of sdh transcription was provided by demonstrating that a TnphoA insertion disrupting sdhB had no effect on the production of SucA by an E. coli cell-extract-directed in vitro transcription/translation system.
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Sequence and linkage analysis of the Coxiella burnetii citrate synthase-encoding gene.
TL;DR: The nucleotide (nt) sequence of the Coxiella burnetii citrate synthase-encoding gene (gltA), previously cloned in Escherichia coli, was determined and represents the first nt sequence analysis of a gene of known function from the obligate intracellular parasite, C. burningetii.
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