Robert A. Bermel
Cleveland Clinic
154 Papers
280 Citations
Robert A. Bermel is an academic researcher from Cleveland Clinic. The author has contributed to research in topics: Medicine & Multiple sclerosis. The author has an hindex of 27, co-authored 100 publications. Previous affiliations of Robert A. Bermel include State University of New York System & University at Buffalo.
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Papers
The measurement and clinical relevance of brain atrophy in multiple sclerosis.
Robert A. Bermel,Rohit Bakshi +1 more
TL;DR: The rate of atrophy among phenotypes for multiple sclerosis, the clinical relevance of brain atrophy, and the effect of disease-modifying treatments on its progression are summarized.
474
Retinal thickness measured with optical coherence tomography and risk of disability worsening in multiple sclerosis: a cohort study
Elena H. Martinez-Lapiscina,Sam Arnow,James A. Wilson,Shiv Saidha,Jana Lizrova Preiningerova,Timm Oberwahrenbrock,Alexander U. Brandt,Luis E. Pablo,Simone Guerrieri,Ines Gonzalez,Olivier Outteryck,Ann Kristin Mueller,P. Albrecht,Wesley Chan,Sebastian Lukas,Lisanne J. Balk,Clare L. Fraser,Jette L. Frederiksen,Jennifer Resto,Teresa C. Frohman,Christian Cordano,Irati Zubizarreta,Magi Andorra,Bernardo Sanchez-Dalmau,Albert Saiz,Robert A. Bermel,Alexander Klistorner,Axel Petzold,Sven Schippling,Fiona Costello,Orhan Aktas,Patrick Vermersch,Celia Oreja-Guevara,Giancarlo Comi,Letizia Leocani,Elena García-Martín,Friedemann Paul,Eva Havrdova,Elliot M. Frohman,Laura J. Balcer,Laura J. Balcer,Ari J. Green,Peter A. Calabresi,Pablo Villoslada,Pablo Villoslada +44 more
TL;DR: The results provide evidence of the usefulness of monitoring peripapillary retinal nerve fibre layer thickness by OCT for prediction of the risk of disability worsening with time in patients with multiple sclerosis.
How patients with multiple sclerosis acquire disability
Fred D. Lublin,Dieter A. Häring,Habib Ganjgahi,Alex Ocampo,Farhad Hatami,Jelena Čuklina,Piet Aarden,Frank Dahlke,Douglas L. Arnold,Heinz Wiendl,Tanuja Chitnis,Thomas E. Nichols,Bernd C. Kieseier,Robert A. Bermel +13 more
TL;DR: It is confirmed that relapses contribute to the accumulation of disability, primarily early in multiple sclerosis.
276
T2 Hypointensity in the Deep Gray Matter of Patients With Multiple Sclerosis: A Quantitative Magnetic Resonance Imaging Study
Rohit Bakshi,Ralph H.B. Benedict,Robert A. Bermel,Shelton D. Caruthers,Srinivas R. Puli,Christopher W. Tjoa,Andrew J. Fabiano,Lawrence Jacobs +7 more
TL;DR: Gray matter T2 hypointensity in MS is associated with brain atrophy and is a stronger predictor of disability and clinical course than are conventional MRI findings, and results suggest that pathologic iron deposition is a surrogate marker of the destructive disease process.
243
Phase 2 trial of ibudilast in progressive multiple sclerosis
Robert J. Fox,Christopher S. Coffey,Robin Conwit,Merit Cudkowicz,Trevis Gleason,Andrew D. Goodman,Eric C. Klawiter,K. Matsuda,Michelle McGovern,Robert T. Naismith,Akshata Ashokkumar,Janel Barnes,Dixie Ecklund,Elizabeth A. Klingner,Maxine Koepp,Jeffrey D. Long,Sneha Natarajan,Brenda Thornell,Jon W. Yankey,Robert A. Bermel,J. P. Debbins,X. Huang,P. Jagodnik,Mark J. Lowe,Kunio Nakamura,S. Narayanan,Kenneth Earl Sakaie,B. Thoomukuntla,X. Zhou,Stephen Krieger,Enrique Alvarez,Michelle L Apperson,Khurram Bashir,Bruce A. Cohen,P. K. Coyle,Silvia Delgado,L. D. Dewitt,A. Flores,Barbara Giesser,Myla D. Goldman,Burk Jubelt,Neil Lava,Sharon G. Lynch,Harold L. Moses,Daniel Ontaneda,Jai Perumal,Michael K. Racke,Michael K. Racke,Pavle Repovic,Claire S Riley,Christopher Severson,Shlomo Shinnar,Valerie Suski,Bianca Weinstock-Guttman,Vijayshree Yadav,Aram Zabeti +55 more
TL;DR: In a phase 2 trial involving patients with progressive multiple sclerosis, ibudilast was associated with slower progression of brain atrophy than placebo but was associatedWith higher rates of gastrointestinal side effects, headache, and depression.