Rivka L. Glaser
Stevenson University
18 Papers
153 Citations
Rivka L. Glaser is an academic researcher from Stevenson University. The author has contributed to research in topics: Sperm & Biology. The author has an hindex of 9, co-authored 15 publications. Previous affiliations of Rivka L. Glaser include Johns Hopkins University School of Medicine & Johns Hopkins University.
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Papers
Advancing age has differential effects on DNA damage, chromatin integrity, gene mutations, and aneuploidies in sperm
Andrew J. Wyrobek,B. Eskenazi,Susan L. Young,Norman Arnheim,Irene Tiemann-Boege,Ethylin Wang Jabs,Rivka L. Glaser,F. S. Pearson,Donald P. Evenson +8 more
TL;DR: There are multiple spermatogenic targets for genomically defective sperm with substantially variable susceptibilities to age, and it is predicted that as healthy males age, they have decreased pregnancy success with trends beginning in their early reproductive years, increased risk for producing offspring with achondroplasia mutations, and risk of fathering offspring with Apert syndrome.
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The Paternal-Age Effect in Apert Syndrome Is Due, in Part, to the Increased Frequency of Mutations in Sperm
Rivka L. Glaser,Karl W. Broman,Rebecca L. Schulman,B. Eskenazi,Andrew J. Wyrobek,Ethylin Wang Jabs +5 more
TL;DR: It was shown that the number of sperm with mutations increased in the oldest age groups among men who did not have a child with AS, and contributing factors to the paternal-age effect may include selection and a higher number of mutant sperm in a subset of men ascertained because they had a children with AS.
Advancing age has differential effects on DNA damage, chromatin integrity, gene mutations, and aneuploidies in sperm
Andrew J. Wyrobek,B. Eskenazi,Susan L. Young,Norman Arnheim,Irene Tiemann-Boege,Ethylin Wang Jabs,Rivka L. Glaser,F. S. Pearson,Donald P. Evenson +8 more
TL;DR: The investigators examined the effects of advancing male age on multiple genomic defects in sperm, chromatin integrity, gene mutations, and numeric chromosomal abnormalities and found that older men do not seem to be at increased risk of trisomic or triploid pregnancies.
Abnormal sterol metabolism in a patient with Antley-Bixler syndrome and ambiguous genitalia
Richard I. Kelley,Richard I. Kelley,Lisa E. Kratz,Lisa E. Kratz,Rivka L. Glaser,Michael L. Netzloff,Linda Miller Wolf,Ethylin Wang Jabs +7 more
TL;DR: In this article, the authors evaluated sterol metabolism in lymphoblast cell lines from an ABS patient without a known FGFR2 mutation and from a patient with an FGFR 2 mutation and ABS-like manifestations.
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Rapid Publication Abnormal Sterol Metabolism in a Patient With Antley-Bixler Syndrome and Ambiguous Genitalia
Richard I. Kelley,Lisa E. Kratz,Rivka L. Glaser,Michael L. Netzloff,Linda Miller Wolf,Ethylin Wang Jabs +5 more
- 01 Jan 2002
TL;DR: The results suggest that ABS can occur in a patient with an intrinsic defect of cholesterol biosynthesis at the level of lanosterol 14-alpha-demethylase, although the genetic nature of the deficiency remains to be determined.
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