Riva C. Marcus
Columbia University
11 Papers
291 Citations
Riva C. Marcus is an academic researcher from Columbia University. The author has contributed to research in topics: Optic chiasm & Retina. The author has an hindex of 10, co-authored 11 publications.
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Papers
Eph family receptors and their ligands distribute in opposing gradients in the developing mouse retina.
TL;DR: The results support an intraretinal role for Eph family members in addition to their previously proposed role in the development of retinotectal topography, and suggest that each subclass specifies positional information along independent retinal axes.
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Dorsal-ventral patterning defects in the eye of BF-1-deficient mice associated with a restricted loss of shh expression.
TL;DR: Findings suggest that shh produced at this site plays a role in patterning the developing eye, and that Sonic hedgehog (shh) expression within the ventral telencephalic neuroepithelium is specifically lost in the BF-1(-/-) mutant.
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Foxd1 is required for proper formation of the optic chiasm
Eloisa Herrera,Riva C. Marcus,Suzanne C. Li,Scott E. Williams,Lynda Erskine,Eseng Lai,Carol A. Mason +6 more
TL;DR: Foxd1 plays a dual role in the establishment of the binocular visual pathways: first, in specification of the VT retina, acting upstream of proteins directing the ipsilateral pathway; and second, in the patterning of the developing ventral diencephalon where the optic chiasm forms.
118
Crossed and uncrossed retinal axons respond differently to cells of the optic chiasm midline in vitro
TL;DR: Retinal explants were cocultured with cells dissociated from the chiasmatic midline, demonstrating that cues for divergence derive from cells resident to the chiasm and suggesting that cellular interactions among resident midline cells are required to produce these cues.
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Domains of Regulatory Gene Expression and the Developing Optic Chiasm: Correspondence With Retinal Axon Paths and Candidate Signaling Cells
Riva C. Marcus,Kenji Shimamura,David W. Sretavan,Eseng Lai,John L.R. Rubenstein,Carol A. Mason +5 more
TL;DR: The hypothesis that molecularly distinct, longitudinally aligned domains in the forebrain regulate the pattern of retinal axon projections in the developing hypothalamus is supported.
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