Rikard Holmdahl
Karolinska Institutet
674 Papers
7.3K Citations
Rikard Holmdahl is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Arthritis & T cell. The author has an hindex of 91, co-authored 644 publications. Previous affiliations of Rikard Holmdahl include Umeå University & University of Erlangen-Nuremberg.
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Papers
Role of anti-hinge antibodies in therapeutic cleavage of IgG: response to Drs. Lutz and Fumia
TL;DR: The potential of targeting antibodies with enzymes derived from group A streptococci as a mode of immunotherapy for IgG-mediated autoimmune diseases is described.
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An encephalomyelitis-specific locus on chromosome 16 in mouse controls disease development and expression of immune-regulatory genes.
Therese Lindvall,Kutty Selva Nandakumar,Kutty Selva Nandakumar,Kimia Yousefi,Rikard Holmdahl,Rikard Holmdahl,Åsa Andersson +6 more
TL;DR: Flow cytometry analyses of expression of two candidate genes within the linked locus demonstrated a significantly lower expression of CD200 on CD4+ T cells and higher expression of BTLA on B cells from the congenic mice.
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S188 collagen antibody-induced arthritis evokes persistent allodynia with a transient prostaglandin dependence and spinal astrocyte involvement in the “post-inflammatory” phase
Duygu B. Bas,S. Jie,A. Baharpoor,Katalin Sandor,J. Pettersson,Simone Codeluppi,Rikard Holmdahl,Kutty Selva Nandakumar,Camilla I. Svensson +8 more
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Collagen antibody-induced arthritis (CAIA) leads to evoked and ongoing persistent pain-like behavior, but transient joint inflammation
Katalin Sandor,Kutty Selva Nandakumar,Rikard Holmdahl,M. Björnholm,R Tom,A. Krook,Camilla I. Svensson +6 more
TL;DR: This study demonstrates that CAIA generates robust and highly reproducible hypersensitivity, making this model suitable for studies of joint pain driven by antibody-mediated inflammation, both during peak and remittent phases of RA.
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Effects on experimental allergic neuritis in rats by in vivo treatment with monoclonal anti-T-cell antibodies.
TL;DR: Effects on experimental allergic neuritis in rats by in vivo treatment with monoclonal anti-T-cell antibodies are studied.
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