Rikard Holmdahl
Karolinska Institutet
674 Papers
7.3K Citations
Rikard Holmdahl is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Arthritis & T cell. The author has an hindex of 91, co-authored 644 publications. Previous affiliations of Rikard Holmdahl include Umeå University & University of Erlangen-Nuremberg.
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Papers
Pharmacological Potential of NOX2 Agonists in Inflammatory Conditions
TL;DR: New insights into the role of reactive oxygen species (ROS) show that activators of the phagocyte NADPH oxidase 2 (NOX2) complex have the potential to be therapeutic in autoimmune and inflammatory conditions.
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Increased levels of prolactin during, but not after, the immunisation with rat collagen ii enhances the course of arthritis in dba/1 mice
TL;DR: The results indicate that PRL has different effects during early and late stages of the development of collagen II-induced arthritis, but treatment at later stages tended to cause exacerbation.
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TNF production in macrophages is genetically determined and regulates inflammatory disease in rats.
Alan Gillett,Monica Marta,Tao Jin,Jonatan Tuncel,Patrick Leclerc,Rita Nohra,Stefan Lange,Rikard Holmdahl,Tomas Olsson,Robert A. Harris,Maja Jagodic +10 more
TL;DR: The decreased TNF potential and reduced proinflammatory macrophage phenotype in congenic rats was also associated with reduced clinical severity in experimental autoimmune encephalomyelitis, pristane-induced arthritis and sepsis experimental models.
Identification of Genetic Regions of Importance for Reproductive Performance in Female Mice
Maria Liljander,Mary-Ann Sällström,Sara Andersson,Patrik Wernhoff,Åsa Andersson,Rikard Holmdahl,Ragnar Mattsson +6 more
TL;DR: This study focused on the identification of genetic regions, quantitative trait loci (QTL), which affect the breeding capacity of female mice, and identified polymorphic microsatellite markers for the mouse strains used.
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Oxazole-modified glycopeptides that target arthritis-associated class II MHC Aq and DR4 proteins
Ida E. Andersson,Tsvetelina Batsalova,Balik Dzhambazov,Lotta Edvinsson,Rikard Holmdahl,Jan Kihlberg,Jan Kihlberg,Anna Linusson +7 more
TL;DR: This work contributes to the development of an altered glycopeptide for inducing immunological tolerance in CIA, with the long-term goal of developing a therapeutic vaccine for treatment of RA.