Richard S. Smith
Brigham and Women's Hospital
13 Papers
82 Citations
Richard S. Smith is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Aminophylline & Population. The author has an hindex of 9, co-authored 13 publications. Previous affiliations of Richard S. Smith include University of Maryland, Baltimore & Wake Forest University.
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Papers
Global survey of diversity among environmental saltwater Bacteriovoracaceae.
Silvia A. Pineiro,O. Colin Stine,Ashvini Chauhan,Susan R. Steyert,Richard S. Smith,Henry N. Williams +5 more
TL;DR: The results of this study reveal the saltwater Bx to be phylogenetically and environmentally more diverse than was previously known.
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Effect of Hydrocortisone on Immunoglobulin Synthesis and Secretion by Human Peripheral Lymphocytes in vitro
TL;DR: It is demonstrated that human peripheral lymphocytes cultured in vitro interact with hydrocortisone to modify Ig synthesis, and the only Ig formed was IgG; a β-globulin was also formed (radioimmunoelectrophoresis).
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Evolutionary genetics of the human Rh blood group system.
George H. Perry,Yali Xue,Richard S. Smith,Wynn K. Meyer,Minal Çalışkan,Omar Yanez-Cuna,Omar Yanez-Cuna,Arthur Lee,Maria Gutierrez-Arcelus,Maria Gutierrez-Arcelus,Carole Ober,Edward J. Hollox,Chris Tyler-Smith,Charles Lee +13 more
TL;DR: This study used new molecular and genomic data generated from four HapMap population samples to test the idea that positive selection for an as-of-yet unknown fitness benefit of the RHD deletion may have offset the otherwise negative fitness effects of hemolytic disease of the newborn, and found no evidence that positive natural selection affected the frequency of theRHD deletion.
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Sequence analysis of HSPA1A and HSPA1B in a multi-ethnic study population.
Richard S. Smith,Deborah A. Meyers,Stephen P. Peters,Wendy C. Moore,Sally A Wenzel,Eugene R. Bleecker,Gregory A. Hawkins +6 more
TL;DR: Although similar in sequence, HSPAIA and HSPAIB do not share common patterns of polymorphisms, and two-thirds of the polymorphisms reported in dbSNP were not identified in the authors' screening panel.
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Effects of pokeweed mitogen, cholera toxin and prostaglandin E1 on immunoglobulin production and cyclic AMP levels in tonsillar lymphocytes.
TL;DR: Lymphocytes from human tonsils and adenoids and three compounds – pokeweed mitogen, cholera toxin and prostaglandin E1 – were used to study the relationship of immunoglobulin (Ig) synthesis and secretion and intra-cellular levels of cyclic 3′5′-adenosine monophosphate (cAMP).
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