Richard P. Novick
New York University
297 Papers
5K Citations
Richard P. Novick is an academic researcher from New York University. The author has contributed to research in topics: Plasmid & Biology. The author has an hindex of 99, co-authored 295 publications. Previous affiliations of Richard P. Novick include Centers for Disease Control and Prevention & Spanish National Research Council.
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Papers
The toxic shock syndrome exotoxin structural gene is not detectably transmitted by a prophage
Barry N. Kreiswirth,Sven Löfdahl,Marsha J. Betley,Mary O'Reilly,Patrick M. Schlievert,Merlin S. Bergdoll,Richard P. Novick +6 more
TL;DR: It is shown here that TSSE is not demonstrably transferred by lysogeny; moreover, the gene is cloned and the cloned product is serologically and biologically indistinguishable from the native protein, and that the TSSE determinant is associated with a larger DNA segment that is absent or rearranged in TSSE− strains.
1.4K
Autoinduction and signal transduction in the regulation of staphylococcal virulence
TL;DR: This review is an attempt to integrate a large body of data into the beginnings of a model that will hopefully help to guide research towards a full‐scale test of the regulatory agenda of Staphylococcus aureus.
1.3K
Synthesis of staphylococcal virulence factors is controlled by a regulatory RNA molecule.
Richard P. Novick,H. F. Ross,Steven J. Projan,John Kornblum,Barry N. Kreiswirth,Soraya L. Moghazeh +5 more
TL;DR: It is shown that the cloned RNAIII determinant restores both positive and negative regulatory functions of agr to an agr‐null strain and that the RNA itself, rather than any protein, is the effector molecule.
1.1K
Quorum Sensing in Staphylococci
TL;DR: It is suggested that agr autoactivation, unlike classical enzyme induction, can occur under suboptimal conditions and can distinguish self from non-self by inducing an exclusive and coordinated population wide response.
960
Bacterial Interference Caused by Autoinducing Peptide Variants
TL;DR: Cross-inhibition of gene expression represents a type of bacterial interference that could be correlated with the ability of one strain to exclude others from infection or colonization sites, or both.
849