Richard H. Adamson
National Institutes of Health
114 Papers
2.1K Citations
Richard H. Adamson is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Heterocyclic amine & Excretion. The author has an hindex of 37, co-authored 114 publications. Previous affiliations of Richard H. Adamson include Mount Desert Island Biological Laboratory & American Beverage Association.
Chat about Author
Papers
Synthesis, purification and mutagenicity of 2-hydroxyamino-3-methylimidazolo[4,5-f] quinoline
Elizabeth G. Snyderwine,Peter P. Roller,Peter J. Wirth,Richard H. Adamson,Shigeaki Sato,Snorri S. Thorgeirsson +5 more
TL;DR: The data confirm that N-hydroxy-IQ is a mutagenic metabolite of IQ and further implicate the hydroxylamine in the carcinogenicity of IQ.
30
Distribution and Effects of DDT in the Pregnant Rabbit
TL;DR: P'-DDT treatment of pregnant rabbits at doses of 10 and 50 mg/kg caused an increased incidence of prematurity, an increase in the number of foetal resorptions and a decrease infoetal weight, while exposure in vitro to levels as high as 100 μg/ml caused no abnormalities.
30
•Journal Article
DNA Polymerases of Walker 256 Carcinosarcoma
TL;DR: A study of the DNA polymerases of Walker 256 carcinosarcoma found an RNA-directed DNA polymerase associated with RNA tumor viruses, which suggests that their in vivo antitumor properties were probably mediated through some mechanism of action other than inhibition of this enzyme.
29
Apparent lack of interaction between dimethyl sulfoxide (dmso) and a variety of drugs.
TL;DR: DMSO appears to be a very good solvent with little or no effect on pharmacological action and preliminary tests failed to indicate that DMSO possesses local anesthetic or analgetic action.
28
Short-term carcinogenicity testing of 2-amino-1-methyl-6-phenylimidazo[4, 5-b]pyridine (PhIP) and 2-amino-3-methylimidazo[4, 5-f]quinoline (IQ) in Eμ-pim-1 transgenic mice
Ilona Kryspin Sørensen,Alicja Mortensen,Eva Kristiansen,Coen F. van Kreijl,Richard H. Adamson,Snorri S. Thorgeirsson +5 more
TL;DR: The results suggest that the transgenic E(mu)-pim-1 mouse may be a useful model for short-term carcinogenicity screening of potential genotoxic carcinogens having the lymphoid system as target tissue.
27