Richard C. Gerkin
Arizona State University
86 Papers
166 Citations
Richard C. Gerkin is an academic researcher from Arizona State University. The author has contributed to research in topics: Biology & Odor. The author has an hindex of 22, co-authored 70 publications. Previous affiliations of Richard C. Gerkin include Carnegie Mellon University & University of California, San Diego.
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Papers
Coactivation and timing-dependent integration of synaptic potentiation and depression
TL;DR: The results indicate that the signaling machinery underlying spike timing–dependent plasticity (STDP) may be separated into functional modules that are sensitive to the spatiotemporal dynamics (rather than the amount of calcium influx).
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Predicting human olfactory perception from chemical features of odor molecules
Andreas Keller,Richard C. Gerkin,Yuanfang Guan,Amit Dhurandhar,Gábor Turu,Bence Szalai,Joel D. Mainland,Joel D. Mainland,Yusuke Ihara,Yusuke Ihara,Chung Wen Yu,Russell D. Wolfinger,Celine Vens,Leander Schietgat,Kurt De Grave,Raquel Norel,Gustavo Stolovitzky,Gustavo Stolovitzky,Guillermo A. Cecchi,Leslie B. Vosshall,Leslie B. Vosshall,Pablo Meyer,Pablo Meyer +22 more
TL;DR: Results of a crowdsourcing competition show that it is possible to accurately predict and reverse-engineer the smell of a molecule, with a predictive accuracy that closely approaches a key theoretical limit.
More than smell. COVID-19 is associated with severe impairment of smell, taste, and chemesthesis
Valentina Parma,Kathrin Ohla,Maria G. Veldhuizen,Masha Y. Niv,Christine E. Kelly,Alyssa J. Bakke,Keiland W. Cooper,Cédric Bouysset,Nicola Pirastu,Michele Dibattista,Rishemjit Kaur,Marco Tullio Liuzza,Marta Yanina Pepino,Veronika Schöpf,Veronica Pereda-Loth,Shannon B. Olsson,Richard C. Gerkin,Paloma Rohlfs Domínguez,Javier Albayay,Michael C. Farruggia,Surabhi Bhutani,Alexander Fjaeldstad,Ritesh Kumar,Anna Menini,Moustafa Bensafi,Mari Sandell,Iordanis Konstantinidis,Antonella Di Pizio,Federica Genovese,Lina Öztürk,Thierry Thomas-Danguin,Johannes Frasnelli,Sanne Boesveldt,Ozlem Saatci,Luis R. Saraiva,Cailu Lin,Jérôme Golebiowski,Liang-Dar Hwang,Mehmet Hakan Ozdener,M.D. Guàrdia,Christophe Laudamiel,Marina Ritchie,Jan Havlíček,Denis Pierron,Eugeni Roura,Marta Navarro,Alissa A. Nolden,Juyun Lim,Katherine L. Whitcroft,Lauren R. Colquitt,Camille Ferdenzi,Evelyn V. Brindha,Aytug Altundag,Alberto Macchi,Alexia Nunez-Parra,Zara M. Patel,Sébastien Fiorucci,Carl Philpott,Barry C. Smith,Johan N. Lundström,Carla Mucignat,Jane K. Parker,Mirjam van den Brink,Michael Schmuker,Florian Ph. S. Fischmeister,Thomas Heinbockel,Vonnie D. C. Shields,Farhoud Faraji,Enrique Santamaría,William E.A. Fredborg,Gabriella Morini,Jonas Olofsson,Maryam Jalessi,Noam Karni,Anna D'Errico,Rafieh Alizadeh,Robert Pellegrino,Pablo Meyer,Caroline Huart,Ben Chen,Graciela M. Soler,Mohammed K. Alwashahi,Olagunju Abdulrahman,Antje Welge-Lüssen,Pamela Dalton,Jessica Freiherr,Carol H. Yan,Jasper H. B. de Groot,Vera V. Voznessenskaya,Hadar Klein,Jingguo Chen,Masako Okamoto,Elizabeth Sell,Preet Bano Singh,Julie Walsh-Messinger,Nicholas Archer,Sachiko Koyama,Vincent Deary,S. Craig Roberts,Huseyin Yanik,Samet Albayrak,Lenka Martinec Novákov,Ilja Croijmans,Patricia Portillo Mazal,Shima T. Moein,Eitan Margulis,Coralie Mignot,Sajidxa Mariño,Dejan Georgiev,Pavan Kumar Kaushik,Bettina Malnic,Hong Wang,Shima Seyed-Allaei,Nur Yoluk,Sara Razzaghi,Jeb M. Justice,Diego Restrepo,Julien W. Hsieh,Danielle R. Reed,Thomas Hummel,Steven D. Munger,John E. Hayes +121 more
TL;DR: The results show that COVID-19-associated chemosensory impairment is not limited to smell, but also affects taste and chemesthesis, and suggest that SARS-CoV-2 infection may disrupt sensory-neural mechanisms.
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Calcium Time Course as a Signal for Spike-Timing–Dependent Plasticity
TL;DR: This work presents a set of model biochemical detectors, based on plausible molecular pathways, which make direct use of the time course of the calcium signal to reproduce these experimental STDP results, and provides computational evidence that small changes in the properties of back-propagation of action potentials or in synaptic dynamics can alter the calcium time course in ways that will significantly affect STDP induction by any detector based exclusively on postsynaptic calcium.
Recent smell loss is the best predictor of COVID-19 among individuals with recent respiratory symptoms.
Richard C. Gerkin,Kathrin Ohla,Maria G. Veldhuizen,Dr. Paule V. Joseph,Christine E. Kelly,Alyssa J. Bakke,Kimberley E. Steele,Michael C. Farruggia,Robert Pellegrino,Marta Yanina Pepino,Cédric Bouysset,Graciela M. Soler,Veronica Pereda-Loth,Michele Dibattista,Keiland W. Cooper,Ilja Croijmans,Antonella Di Pizio,Mehmet Hakan Ozdener,Alexander Fjaeldstad,Cailu Lin,Mari Sandell,Preet Bano Singh,V. Evelyn Brindha,Shannon B. Olsson,Luis R. Saraiva,Gaurav Ahuja,Mohammed K. Alwashahi,Surabhi Bhutani,Anna D'Errico,Marco Aurélio Fornazieri,Jérôme Golebiowski,Liang-Dar Hwang,Lina Öztürk,Eugeni Roura,Sara Spinelli,Katherine L. Whitcroft,Farhoud Faraji,Florian Ph. S. Fischmeister,Thomas Heinbockel,Julien W. Hsieh,Caroline Huart,Iordanis Konstantinidis,Anna Menini,Gabriella Morini,Jonas Olofsson,Carl Philpott,Denis Pierron,Vonnie D. C. Shields,Vera V. Voznessenskaya,Javier Albayay,Aytug Altundag,Moustafa Bensafi,María Adelaida Bock,Orietta Calcinoni,William E.A. Fredborg,Christophe Laudamiel,Juyun Lim,Johan N. Lundström,Alberto Macchi,Pablo Meyer,Shima T. Moein,Enrique Santamaría,Debarka Sengupta,Paloma Rohlfs Domínguez,Huseyin Yanik,Thomas Hummel,John E. Hayes,Danielle R. Reed,Masha Y. Niv,Steven D. Munger,Valentina Parma +70 more
TL;DR: In this paper, the authors investigated whether olfactory loss is a reliable predictor of COVID-19 using a crowdsourced questionnaire in 23 languages to assess symptoms in individuals self-reporting recent respiratory illness.