Renée Fauchet
University of Rennes
135 Papers
2.2K Citations
Renée Fauchet is an academic researcher from University of Rennes. The author has contributed to research in topics: Human leukocyte antigen & Antigen. The author has an hindex of 42, co-authored 135 publications. Previous affiliations of Renée Fauchet include French Institute of Health and Medical Research & University of Rennes 1.
Chat about Author
Papers
HLA-G protein expression is not induced during malignant transformation.
Céline Pangault,Laurence Amiot,Sylvie Caulet-Maugendre,Francis Brasseur,F. Burtin,Valérie Guilloux,Bernard Drenou,Renée Fauchet,M. Onno +8 more
TL;DR: HLA-G is not a marker of malignant cells but appears as a gene expressed in tumor-associated macrophages and dendritic cells, preferentially in those recruited in lung carcinomas, suggesting that specific environmental factors around lung tumors could be involved in the induction of HLA- G protein expression.
64
HLA-G and lymphoproliferative disorders.
Laurence Amiot,Gaëlle Le Friec,Yasmine Sebti,Bernard Drenou,Céline Pangault,Valérie Guilloux,Xavier Leleu,Marc Bernard,Thierry Facon,Renée Fauchet +9 more
TL;DR: Investigations in lymphoproliferative disorders show a frequent and variable distribution of alternatively spliced HLA-G mRNA isoforms, a rare cell surface expression in diffuse large cell lymphomas with HLA class I loss, and an increased serum level of sHLA-G.
56
Idiopathic hemochromatosis: A study of biochemical expression in 247 heterozygous members of 63 families: Evidence for a single major HLA-linked gene
M. Simon,Renée Fauchet,Hespel Jp,Carole Beaumont,Pierre Brissot,B. Hery,Y Hita de Nercy,B. Genetet,Michel Bourel +8 more
TL;DR: It is concluded that idiopathic hemochromatosis is determined by two homologous alleles in accordance with the classical mode of recessive inheritance.
56
MHC class II‐mediated apoptosis of mature dendritic cells proceeds by activation of the protein kinase C‐δ isoenzyme
Nicolas Bertho,Vincent Blancheteau,Niclas Setterblad,Béatrice Laupeze,Janet M. Lord,Bernard Drenou,Laurence Amiot,Dominique Charron,Renée Fauchet,Nuala Mooney +9 more
TL;DR: The lifespan of the mature DC could be controlled by signals generated in the course of antigen presentation, and thereby prevent DC persistence and prolonged stimulation of T and B lymphocytes.
Multidrug resistance protein (MRP) activity in normal mature leukocytes and CD34-positive hematopoietic cells from peripheral blood.
Béatrice Laupeze,Laurence Amiot,Léa Payen,Bernard Drenou,Jean Marc Grosset,Gustav Lehne,Renée Fauchet,Olivier Fardel +7 more
TL;DR: Mature leukocytes display basal constitutive MRP-related transport activity regardless of cell lineage and likely related to MRP1 expression whereas higher MRP -related efflux can be detected in peripheral CD34 hematopoietic cells.
53