Rene Heils
Hamburg University of Technology
11 Papers
59 Citations
Rene Heils is an academic researcher from Hamburg University of Technology. The author has contributed to research in topics: Reactive distillation & Fractionating column. The author has an hindex of 7, co-authored 11 publications.
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Papers
Integration of Enzymatic Catalysts in a Reactive Distillation Column with Structured Packings
TL;DR: In this paper, a special type of biocatalytic coating for commercially available structured packings was developed to enable enzymatic reactions in reactive distillation columns, which can be stored for at least 50 days at room temperature without any significant loss of enzyme activity.
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Enzymatic Reactive Distillation: Kinetic Resolution of rac-2-Pentanol with Biocatalytic Coatings on Structured Packings
Rene Heils,Jan-Hendrik Jensen,Steffen Wichert,Natalie Behrens,Mario Fabuel-Ortega,Andreas Liese,Irina Smirnova +6 more
TL;DR: An enantioselective biocatalytic reaction was carried out for the first time in a fully integrated batch reactive distillation setup to allow reproducible coatings which also can be applied on larger surfaces.
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Integration of Enzymatic Catalysts in a Continuous Reactive Distillation Column: Reaction Kinetics and Process Simulation
Rene Heils,Alexander Niesbach,Matthias Wierschem,Dierk Claus,Sebastian Soboll,Philip Lutze,Irina Smirnova +6 more
TL;DR: This work presents a feasibility study for an enzymatic reaction in a continuously operated reactive distillation column and describes the reaction kinetics by means of the Michaelis–Menten double-substrate kinetic model in combination with the Arrhenius model.
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In situ production and renewal of biocatalytic coatings for use in enzymatic reactive distillation
TL;DR: In this paper, an in situ production method for biocatalytic coatings on structured packings is presented which enables production and renewal of the catalytic structures in place, i.e. without disassembly of the column internals.
13
In Situ Separation of the Chiral Target Compound (S)-2-Pentanol in Biocatalytic Reactive Distillation
Steffen Kühn,Gerrit Sluyter,Marc-Andreas Christlieb,Rene Heils,Anne Stöbener,Joscha Kleber,Irina Smirnova,Andreas Liese +7 more
TL;DR: In situ separation of a chiral target compound is realized for the first time as distillate on top of an integrated biocatalytic batch reactive distillation column and the reaction system is the racemic resolution of (S)-2-pentanol in a transesterification with propyl butyrate.
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