Renae Deans
Royal Brisbane and Women's Hospital
19 Papers
160 Citations
Renae Deans is an academic researcher from Royal Brisbane and Women's Hospital. The author has contributed to research in topics: Medicine & Renal function. The author has an hindex of 12, co-authored 19 publications. Previous affiliations of Renae Deans include University of Queensland.
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Papers
Pharmacokinetics of Colistin Methanesulfonate and Colistin in a Critically Ill Patient Receiving Continuous Venovenous Hemodiafiltration
Jian Li,Craig R Rayner,Roger L. Nation,Renae Deans,Robert J. Boots,N Widdecombe,Alexandra Douglas,Jeffrey Lipman +7 more
TL;DR: Intravenous colistin methanesulfonate (CMS) is increasingly the last line of defense for multidrug-resistant gram-negative bacteria and is now being used as “salvage” therapy in critically ill patients.
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Augmented creatinine clearance in traumatic brain injury.
Andrew A. Udy,Robert J. Boots,Siva Senthuran,Janine Stuart,Renae Deans,Melissa Lassig-Smith,Jeffrey Lipman +6 more
TL;DR: Augmented CrCls are common in TBI patients receiving active management of CPP and persist even after discontinuation of such therapy, and further work is needed to clarify the impact of such clearances on renally excreted drugs in this setting.
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The Effect of Renal Replacement Therapy and Antibiotic Dose on Antibiotic Concentrations in Critically Ill Patients: Data From the Multinational Sampling Antibiotics in Renal Replacement Therapy Study
Jason A. Roberts,Gavin M. Joynt,Anna Lee,Gordon Y.S. Choi,Rinaldo Bellomo,Salmaan Kanji,Salmaan Kanji,M Yugan Mudaliar,Sandra L. Peake,Sandra L. Peake,Dianne P Stephens,Fabio Silvio Taccone,Marta Ulldemolins,Miia Valkonen,Julius Agbeve,João P Baptista,Vasileios Bekos,Clément Boidin,Clément Boidin,Alexander Brinkmann,Luke Buizen,Pedro Castro,C Louise Cole,C Louise Cole,Jacques Creteur,Jan J. De Waele,Renae Deans,Glenn M Eastwood,Leslie Escobar,Charles D. Gomersall,Rebecca Gresham,Janattul Ain Jamal,Stefan Kluge,Christina König,Christina König,Vasilios P Koulouras,Melissa Lassig-Smith,Pierre-François Laterre,Katie Lei,Patricia Leung,Jean-Yves Lefrant,Mireia Llaurado-Serra,Ignacio Martin-Loeches,Mohd Basri Mat Nor,Marlies Ostermann,Suzanne L. Parker,Jordi Rello,Darren M. Roberts,Michael S. Roberts,Michael S. Roberts,Brent Richards,Alejandro Rodríguez,Anka C Roehr,Claire Roger,Leonardo Seoane,Leonardo Seoane,Mahipal G. Sinnollareddy,Eduardo Sousa,Dolors Soy,Anna Spring,Therese Starr,Jane Thomas,John D. Turnidge,Steven C. Wallis,Tricia Williams,Tricia Williams,Xavier Wittebole,Xanthi T Zikou,Sanjoy K. Paul,Jeffrey Lipman,Jeffrey Lipman +70 more
TL;DR: In critically ill patients treated with RRT, antibiotic dosing regimens, RRT prescription and eTRCL varied markedly and resulted in highly variable antibiotic concentrations that failed to meet therapeutic targets in many patients.
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Augmented Renal Clearance in Traumatic Brain Injury: A Single-Center Observational Study of Atrial Natriuretic Peptide, Cardiac Output, and Creatinine Clearance
Andrew A. Udy,Paul Jarrett,Melissa Lassig-Smith,Janine Stuart,Therese Starr,Rachel Dunlop,Renae Deans,Jason A. Roberts,Jason A. Roberts,Siva Senthuran,Robert J. Boots,Kavita Bisht,Andrew C. Bulmer,Jeffrey Lipman,Jeffrey Lipman +14 more
TL;DR: The data suggest that ARC is likely to complicate the care of TBI patients with normal plasma creatinine concentrations, and may be driven by associated cardiovascular changes and/or elevated plasma ANP concentrations, however, significant additional research is required to further understand these findings.
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A randomized, controlled pilot clinical trial of cryopreserved platelets for perioperative surgical bleeding: the CLIP-I trial
Michael C. Reade,Denese C. Marks,Rinaldo Bellomo,Renae Deans,Daniel Faulke,John F. Fraser,David Gattas,Anthony Holley,David O. Irving,Lacey Johnson,Bronwyn Pearse,Alistair Royse,Janet Yuen Ha Wong +12 more
TL;DR: Cryopreservation extends platelet shelf life from 5 to 7 days to 2 to 4 years, however, only 73 patients have been transfused cryopreserved PLTs in published randomized controlled trials (RCTs), making safety data insufficient for regulatory approval.
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