Rena N. D'Souza
University of Utah
134 Papers
1K Citations
Rena N. D'Souza is an academic researcher from University of Utah. The author has contributed to research in topics: Odontoblast & Pulp (tooth). The author has an hindex of 46, co-authored 128 publications. Previous affiliations of Rena N. D'Souza include Texas A&M Health Science Center & University of Helsinki.
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Papers
Coordinate patterns of expression of type I and III collagens during mouse development.
Karen Niederreither,Rena N. D'Souza,M Metsäranta,Heidi Eberspaecher,P.D. Toman,Eero Vuorio,B de Crombrugghe +6 more
TL;DR: This comprehensive study of the transcripts of abundantly expressed structural proteins should provide a basis for comparison of other key extracellular matrix molecules and serve as a reference for studies on the patterns of activities of various promoter/enhancer-reporter gene constructions of type I and III collagen genes in transgenic mice.
Expression of Runx2/Cbfa1/Pebp2αA During Angiogenesis in Postnatal Rodent and Fetal Human Orofacial Tissues
Antonius L.J.J. Bronckers,Kenichi Sasaguri,Adriana Cavender,Rena N. D'Souza,Marten A. Engelse +4 more
TL;DR: The data suggest that Runx2 is expressed in a multipotential mesenchymal cell population that gives rise to various osseous and nonosseous cell lineages.
FAM20B-catalyzed glycosaminoglycans control murine tooth number by restricting FGFR2b signaling
Jingyi Wu,Jingyi Wu,Ye Tian,Ye Tian,Lu Han,Lu Han,Chao Liu,Chao Liu,Tianyu Sun,Tianyu Sun,Ling Li,Yanlei Yu,Bikash Lamichhane,Rena N. D'Souza,Sarah E. Millar,Robb Krumlauf,Robb Krumlauf,David M. Ornitz,Jian Q. Feng,Ophir D. Klein,Hu Zhao,Fuming Zhang,Robert J. Linhardt,Xiaofang Wang +23 more
TL;DR: Evidence is presented that disrupting glycosaminoglycans in the dental epithelium of mice by inactivating FAM20B, a xylose kinase essential for GAG assembly, leads to supernumerary tooth formation in a pattern reminiscent of replacement teeth.
Studies on Pax9-Msx1 protein interactions.
TL;DR: The biochemical data, coupled with human genetic studies and expression analysis in a mouse model, indicate a functional relationship between Pax9 and Msx1 during tooth development and there is a physical association between the two proteins.
Pax9's dual roles in modulating Wnt signaling during murine palatogenesis.
TL;DR: It is shown that controlled intravenous delivery of small molecule Wnt agonists specifically blocks the action of Dkks (inhibitors of Wnt signaling) and corrects secondary palatal clefts in Pax9−/− mice.