Regine Witkowski
Humboldt University of Berlin
19 Papers
363 Citations
Regine Witkowski is an academic researcher from Humboldt University of Berlin. The author has contributed to research in topics: Chromosome 7 (human) & Fluorescence in situ hybridization. The author has an hindex of 11, co-authored 19 publications.
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Papers
Recurrent gain of chromosome arm 7q in low-grade astrocytic tumors studied by comparative genomic hybridization.
Evelin Schröck,Collin Blume,Marie-Christine Meffert,Stanislas du Manoir,Wolf Bersch,Marika Kiessling,Tanka Lozanowa,Gundula Thiel,Regine Witkowski,Thomas Ried,Thomas Cremer +10 more
TL;DR: The findings suggest that a gain of 7q is an early event in the initiation of astrocytomas in adult patients, and support the hypothesis that there might be different mechanisms responsible for tumor development.
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Deficiency, transposition, and duplication of one 15q region may be alternatively associated with Prader-Willi (or a similar) syndrome. Analysis of seven cases after varying ascertainment
M. Fraccaro,Orsetta Zuffardi,Emmanuelle Buhler,Albert Schinzel,G. Simoni,Regine Witkowski,E. Bonifaci,D. Caufin,G. Cignacco,N. Delendi,L. Gargantini,T. Losanowa,L. Marca,Eva Ullrich,V. Vigi +14 more
TL;DR: It is concluded that deficiency, transposition, and even duplication of the region(s) 15q11-q13 may all result in a syndrome which is identifiable with or similar to the Prader-Willi syndrome.
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Involvement of chromosome 22 in ependymomas
Catrin Wernicke,Gundula Thiel,Tanka Lozanova,Siegfried Vogel,Dieter Kintzel,Werner Jänisch,Karin Lehmann,Regine Witkowski +7 more
TL;DR: The possible role of chromosome 22 in ependymomas and the usefulness of fluorescence in situ hybridization for cytogenetic analysis in tumor investigation are discussed.
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Numerical aberrations of chromosomes 1, 2, and 7 in astrocytomas studied by interphase cytogenetics
TL;DR: The data suggest that loss of 1p is an early event in the development of juvenile astrocytomas and that trisomy 7 is frequent in malignant tumors and tumors containing a potential of growing malignantly.
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Coamplification of simple repetitive DNA fingerprint fragments and the EGFR gene in human gliomas.
Peter Nürnberg,Hans Zischler,Eike Fuhrmann,Gundula Thiel,Tanka Losanova,Dieter Kinzel,Gunter Nisch,Regine Witkowski,Jörg T. Epplen +8 more
TL;DR: Gain and/or loss of bands or significant band intensity shifts could be demonstrated in the fingerprints of more than 80% of the tumors investigated and a multitude of somatic changes was detected and found to reflect the chromosome alterations identified by parallel karyotype analysis.
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