Regina Ryan
University of New South Wales
4 Papers
4 Citations
Regina Ryan is an academic researcher from University of New South Wales. The author has contributed to research in topics: Biology & Exome. The author has an hindex of 3, co-authored 3 publications.
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Papers
Analysis of 7,815 cancer exomes reveals associations between mutational processes and somatic driver mutations.
Rebecca C. Poulos,Rebecca C. Poulos,Yuen T. Wong,Regina Ryan,Herbert Pang,Jason W. H. Wong,Jason W. H. Wong +6 more
TL;DR: This study provides statistical foundations for hypothesised links between otherwise independent biological processes and uncovers previously unexplored relationships between driver mutations and mutagenic processes during cancer development.
Integrated Genetic, Epigenetic, and Transcriptional Profiling Identifies Molecular Pathways in the Development of Laterally Spreading Tumors
Luke B. Hesson,Benedict Ng,Peter Zarzour,Sameer Srivastava,Sameer Srivastava,Chau To Kwok,Deborah Packham,Andrea Nuñez,Dominik Beck,Regina Ryan,Ashraf Dower,Caroline E. Ford,John E. Pimanda,Mathew A. Sloane,Nicholas J. Hawkins,Michael J. Bourke,Jason W. H. Wong,Robyn L. Ward,Robyn L. Ward +18 more
TL;DR: The finding that LSTs exhibit a mutational load similar to colorectal carcinomas has implications for the validity of molecular biomarkers for assessing cancer risk and integrated omics data identify molecular features associated with noncancerous L STs highlight that mutation load, which is relatively high in Lsts, is a poor predictor of invasive potential.
Synthesis and surface modification of magnetic nanoparticles for potential applications in sarcomas
S. Shahbazi,Xiaochun Wang,Jia-Lin Yang,Xuchuan Jiang,Xuchuan Jiang,Regina Ryan,Aibing Yu,Aibing Yu +7 more
TL;DR: It is found that the readily available IONPs can be taken up by synovial sarcoma and liposarcoma cell lines in the selective histological tumor types; however, they seem highly toxic for fibrous histiocytoma and fibrosarcomA.
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Rapid Protocol Development, Study Startup and Enrolment of a Prospective Study of COVID-19 Vaccination for Patients with Cancer: A Collaborative Approach
Amy Body,Vivienne E. Milch,Lynda M McSorley,Luxi Lal,E. Ahern,Regina Ryan,G. Jones,Dorothy M. K. Keefe,Eva Segelov +8 more
TL;DR: In this article , the authors describe the rapid design and startup of a multicentre study of COVID-19 vaccine response for vulnerable patients with cancer, which is an example of intensive collaboration inspired by the COVID19 pandemic and may serve as an agile research response to real-time public health challenges.