Reet Pai
University of Pittsburgh
10 Papers
5 Citations
Reet Pai is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Cancer & Internal medicine. The author has an hindex of 4, co-authored 7 publications.
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Papers
Super-resolution Imaging Reveals the Evolution of Higher-Order Chromatin Folding in Early Carcinogenesis
Jianquan Xu,Hongqiang Ma,Hongbin Ma,Hongbin Ma,Wei Jiang,Wei Jiang,Christopher A. Mela,Meihan Duan,Meihan Duan,Shimei Zhao,Shimei Zhao,Chenxi Gao,Eun-Ryeong Hahm,Santana M. Lardo,Kris Troy,Ming Sun,Reet Pai,Donna B. Stolz,Lin Zhang,Shivendra V. Singh,Randall E. Brand,Douglas J. Hartman,Jing Hu,Sarah J. Hainer,Yang Liu +24 more
TL;DR: The authors optimise super-resolution microscopy for pathological tissue and discovered a significant decompaction of chromatin folding in early carcinogenesis prior to tumour formation, which may improve cancer diagnosis, risk stratification, and prevention.
Quantitative and Sensitive Detection of Cancer Genome Amplifications from Formalin Fixed Paraffin Embedded Tumors with Droplet Digital PCR
Lincoln Nadauld,John F. Regan,Laura Miotke,Reet Pai,Teri A. Longacre,Shirley S Kwok,Serge Saxonov,James M. Ford,Hanlee P. Ji +8 more
TL;DR: An assay for the fibroblast growth factor receptor 2 gene (FGFR2) that is amplified in a gastric and breast cancers as well as others is designed and successfully utilized ddPCR to ascertain FGFR2 amplifications from FFPE-preserved gastrointestinal adenocarcinomas.
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Smooth muscle tumors of the gastrointestinal tract: an analysis of prognostic features in 407 cases
Lindsay Alpert,Ram Al-Sabti,Rondell P. Graham,Rish K. Pai,Raul S. Gonzalez,Xuefeng Zhang,Vanessa L. Smith,Hanlin L. Wang,Lindsey M Westbrook,John R. Goldblum,Ahmed Bakhshwin,Sindhu Shetty,David S. Klimstra,Jinru Shia,Gokce Askan,Marie E. Robert,Courtney Thomas,Wendy L. Frankel,Mohammed Alsomali,Catherine Hagen,Mohamed E. Mostafa,Michael Feely,Naziheh Assarzadegan,Joseph Misdraji,Angela R. Shih,Diana Agostini-Vulaj,Jeanne M. Meis,Sherry Tang,Deyali Chatterjee,Liang I. Kang,John Hart,Sang Mee Lee,Theresa Smith,Rhonda K. Yantiss,Erika Hissong,Zu-Hua Gao,Jing Bo Wu,Murray B. Resnick,Elizabeth Yiru Wu,Reet Pai,Lei Zhao,Leona A. Doyle,Shefali Chopra,Nicole C. Panarelli,Shaomin Hu,Teri A. Longacre,Shyam S. Raghavan,Gregory Y. Lauwers,Masoumeh Ghayouri,Harry S. Cooper,Rajeswari Nagarathinam,Andrew M. Bellizzi,Sanjay Kakar,Mojgan Hosseini,Juan Rong,Joel K. Greenson,Laura W. Lamps,Zachary Dong,Mary P. Bronner +58 more
TL;DR: It appears that nonesophageal gastrointestinal smooth muscle tumors measuring >10 cm and/or showing ≥3 mitoses/5 mm 2 may behave aggressively, and therefore close clinical follow-up is recommended in these cases.
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Super-resolution imaging reveals the evolution of higher-order chromatin folding in early carcinogenesis
Jianquan Xu,Hongqiang Ma,Hongbin Ma,Hongbin Ma,Wei Jiang,Wei Jiang,Meihan Duan,Meihan Duan,Shimei Zhao,Shimei Zhao,Chenxi Gao,Eun-Ryeong Hahm,Santana M. Lardo,Kris Troy,Ming Sun,Reet Pai,Donna B. Stolz,Shivendra V. Singh,Randall E. Brand,Douglas J. Hartman,Jing Hu,Sarah J. Hainer,Yang Liu +22 more
TL;DR: This study underlines the significance of unfolding higher-order chromatin structure as an enabling characteristic to promote tumorigenesis, which may facilitate the development and evaluation of new preventive strategies.
Complete biochemical response after pulmonary metastasectomy in prostate adenocarcinoma.
TL;DR: This case and others suggest metastasectomy could be considered in cases with solitary metastasis, and physicians should have a careful discussion regarding risks and possible benefits from surgical excision.