Background—Atrial fibrillation (AF) occurs in 20% to 40% of patients after CABG. Identification of patients vulnerable for arrhythmia will allow targeting of those most likely to benefit from prophylactic therapy. The aim of the present study was to evaluate accuracy of a prospectively defined signal-averaged P-wave duration (SAPD) cutoff and additional preoperative characteristics for the prediction of AF after CABG. Methods and Results—Patients undergoing elective isolated CABG were recruited to the present prospective study. SAPD was recorded in all patients. Filtered signals from 3 orthogonal leads were combined in a vector analysis, and total SAPD was measured preoperatively. Postoperative in-hospital AF occurred in 92 (28.2%) of 326 patients. Patients who developed AF were older (65.9 versus 61.7 years of age; P<0.0005) and had longer SAPD (158 versus 145 ms; P<0.0005) than non-AF patients. Incidence of AF increased in patients ≥75 years of age and increased progressively throughout the range of SAP...

Atrial fibrillation after coronary artery bypass surgery: a model for preoperative risk stratification.

Atrial fibrillation (AF) occurs in 20-40% of patients after coronary artery bypass graft surgery (CABG) and contributes to increased morbidity and expenditure after CABG. The limited efficacy of pharmacological treatment to prevent post-CABG AF has stimulated research into alternative prophylactic strategies for the arrhythmia. This article critically reviews the trial evidence in the literature regarding the efficacy of epicardial atrial pacing to prevent post-CABG AF. Thirteen randomised controlled trials of either right, left, or biatrial pacing to prevent post-CABG AF were identified. Overall, prophylactic biatrial epicardial pacing appears to be effective prophylaxis against post-CABG AF and to reduce postoperative hospital stay. The efficacy of single site right or left atrial pacing is less clear. Further data are required to determine both the efficacy of single site atrial pacing and the cost effectiveness of pacing strategies to prevent AF after CABG.

https://heart.bmj.com/content/heartjnl/90/2/129.full.pdf

Atrial pacing for the prevention of atrial fibrillation after coronary artery bypass graft surgery: a review of the literature

Giving IV and oral amiodarone perioperatively for the prevention of postoperative Atrial fibrillation in patients undergoing coronary artery bypass surgery: The GAP study

A 65 year old woman with hypertension and permanent atrial fibrillation had suffered two brief syncopal episodes. She was on losartan, digoxin, and aspirin. The ECG showed atrial fibrillation and incomplete left bundle branch block; the QT interval was 0.36 s and the QTc 0.414 s. The echocardiogram revealed mild dilatation and dysfunction of …

https://heart.bmj.com/content/heartjnl/90/2/133.full.pdf

Spontaneous termination of ventricular fibrillation

Background: The immediate response obtained following intravenous amiodarone administration, has made amiodarone to be the first choice for arrhythmia treatment occurring after coronary artery bypass grafting. However, whether the response is the same with all the patients undergoing coronary artery bypass grafting is unknown. Methods: We investigated the response to amiodarone therapy in diabetic and nondiabetic patients who developed arrhythmia after coronary artery bypass grafting operation. The response to amiodarone therapy in 25 Type II (noninsulin-depending) diabetic patients was compared with that in 25 non-diabetic patients (i.e. controls). Results: In the diabetic group, atrial fibrillation was observed in 19 patients, and premature ventricular contractions and supraventricular tachycardia were observed in 4 and 2 patients, retrospectively. Atrial fibrillation and premature ventricular contractions were observed in 21 and 4 patients in the control group. In case of arrhythmia, the mean heart rate was 140.92±21.73 beats/min and 141.16±20.31 beats/min in diabetic patients, and the control group, respectively. Upon intravenous amiodarone administration, the mean heart rate was decreased to 87.04±6.11 beats/min in diabetic patients and to 85.92±6.86 beats/min in the control group. The mean response time to the amiodarone therapy was statistically significantly different in diabetic patients (20.8±16.95 hours) when compared with the response time in the control group (7.2±2.39 hours) (p<0.05). Conclusion: The response to amiodarone therapy for arrhythmia was found to be delayed in diabetic patients compared with that in non-diabetic patients undergoing coronary artery bypass grafting operation.

/pdf/the-response-to-antiarrhythmia-therapy-with-amiodarone-in-1zk1i5cz3o.pdf

The Response to Antiarrhythmia Therapy with Amiodarone in Diabetic Patients Undergoing Coronary Artery Bypass Grafting

Amiodarone prophylaxis for atrial fibrillation after cardiac surgery.

Handle everyday research tasks with reliable, citation-backed results

Your personal Research Agent to handle research tasks with citation-backed results

Popular Tasks used by Researchers

How can I help with your research?

Meet SciSpace

Get more enhanced response by uploading the PDFs you want me to reference.

No relevant PDFs in your library

SciSpace is the AI research assistant for academics. Run systematic literature reviews on 280M+ papers, and write papers with cited sources. Trusted by 1M+ students, PhDs & researchers.

SciSpace | AI for Research

Analyze PDFs

Code & Manuscripts

Funding & Grants

Literature & Patents

Medical & Clinical Data

Systematic Review

Visualize & Present

Web & Data

Build a Google Scholar-like website for your research.

Build a website

Create charts and images for your research

Create a Chart

Write a paper for submission to a journal

Draft a manuscript

Patent Search

Design eye-catching scientific posters in minutes.

Scientific Poster Generation

Systematic Literature Review

One task is running at the moment. Your messages will be shown right after.

Drag and drop or click here to browse

Loved by <highlight>1 million+</highlight> researchers

Extract a list of specific topics and their sources from unstructured text

Topics

Compare and analyze relevant papers that matches with your search

Papers

Get insights from PDFs and bookmarked papers from your library

My library

Recent searches

Try searching for:

Catch AI-generated content in scholarly and non-scholarly content

{ai} Detector

Ai Writer

Get PDF Summaries, highlighted text explanations 

Chat with PDF

Effortlessly create in-text citations and bibliographies in APA and 2,500 other formats

Citation generator

Get explanations, summaries, and answers on academic papers

Ease up your research workflow with {scispace}'s cohort of exciting AI tools

Elevate your academic writing skills and convey your ideas the way you want

Paraphraser

Explore our range of reading and writing tools

Your file is being prepared and should be ready in a few minutes. If it's a large file, it might take a bit longer. You can close this window, and we'll email you the file when it's done.

You have reached a maximum limit of <strong>{limit}</strong> columns in the table. Remove at least <strong>1</strong> column to add or create another one.

Redle Jd

Author Tools

Chat about Author

Papers

Amiodarone prophylaxis for atrial fibrillation after cardiac surgery.