Rebecca Ingelfinger
Goethe University Frankfurt
5 Papers
2 Citations
Rebecca Ingelfinger is an academic researcher from Goethe University Frankfurt. The author has contributed to research in topics: Angiogenesis & IκB kinase. The author has an hindex of 1, co-authored 3 publications.
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Papers
Unraveling the Pharmacological Potential of Lichen Extracts in the Context of Cancer and Inflammation With a Broad Screening Approach.
Rebecca Ingelfinger,Marina Henke,Luise Roser,Thomas Ulshöfer,Anjuli Calchera,Garima Singh,Michael J. Parnham,Gerd Geisslinger,Gerd Geisslinger,Robert Fürst,Imke Schmitt,Susanne Schiffmann +11 more
TL;DR: Overall, some of the lichen extracts tested in this study exhibit significant pharmacological activity in the context of inflammation and/or cancer, indicating that the group lichen-forming fungi includes promising members for further testing.
Lecanoric acid mediates anti-proliferative effects by an M phase arrest in colon cancer cells.
Luise Roser,Pelin Erkoc,Rebecca Ingelfinger,Marina Henke,Thomas Ulshöfer,Ann-Kathrin Schneider,Volker Laux,Gerd Geisslinger,Imke Schmitt,Robert Fürst,Susanne Schiffmann +10 more
TL;DR: Wang et al. as mentioned in this paper identified lichen metabolites that are responsible for the observed anti-proliferative effects, and suggested lecanoric acid may be a potential new candidate for anti-cancer therapy, because it has anti-plastic effects on cancer cell lines, and does not affect primary immune cells.
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Xenocoumacin 2 reduces protein biosynthesis and inhibits inflammatory and angiogenesis-related processes in endothelial cells
Pelin Erkoc,Michaela Schmitt,Rebecca Ingelfinger,Iris Bischoff-Kont,Larissa Kopp,Helge B. Bode,Susanne Schiffmann,Robert Fürst +7 more
TL;DR: Xenocoumacin (Xcn) 1 and 2 are the major antibiotics produced by the insect-pathogenic bacterium Xenorhabdus nematophila.
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BNO 1095, a Standardized Dry Extract from the Fruits of Vitex agnus-castus, Impairs Angiogenesis-related Endothelial Cell Functions In Vitro.
TL;DR: In this article, the anti-angiogenic properties of Vitex agnus-castus (BNO 1095) extracts were investigated in in vitro and ex-vivo models.
The Microtubule-Targeting Agent Pretubulysin Impairs the Inflammatory Response in Endothelial Cells by a JNK-Dependent Deregulation of the Histone Acetyltransferase Brd4
T. Primke,Rebecca Ingelfinger,Mohammed A. F. Elewa,Igor Macinkovic,Andreas Weigert,Matthias P. Fabritius,Christoph A. Reichel,Angelika Ullrich,Uli Kazmaier,L. Burgers,Robert Fürst +10 more
TL;DR: This study shows that depolymerizing microtubule-targeting agents, in addition to their established effects on leukocytes, also significantly decrease the inflammatory activation of vascular endothelial cells.