Ravi Rai
Utah State University
15 Papers
328 Citations
Ravi Rai is an academic researcher from Utah State University. The author has contributed to research in topics: Aminoglycoside & Neomycin. The author has an hindex of 10, co-authored 15 publications. Previous affiliations of Ravi Rai include Southern Research Institute.
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Papers
Multiple pathways involved in the biosynthesis of anandamide
Jie Liu,Lei Wang,Judith Harvey-White,Bill X. Huang,Hee-Yong Kim,Serge Luquet,Richard D. Palmiter,Gerald Krystal,Ravi Rai,Anu Mahadevan,Raj K. Razdan,George Kunos +11 more
TL;DR: In macrophages, the endotoxin-induced synthesis of anandamide proceeds uniquely through the phospholipase C/phosphatase pathway, and conversion of synthetic NAPE to AEA by brain homogenates from wild-type and NAPE-PLD(-/-) mice can proceed through both the PLC/ph phosphatase and Abdh4 pathways.
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Application of the synthetic aminosugars for glycodiversification: synthesis and antimicrobial studies of pyranmycin.
Bryan Elchert,Jie Li,Jinhua Wang,Yu Hui,Ravi Rai,Roger Ptak,Priscilla Ward,Jon Y. Takemoto,Mekki F. Bensaci,Cheng-Wei Tom Chang +9 more
TL;DR: Although the antibacterial activity of pyranmycins against aminoglycoside resistant bacteria is less than expected, the synthetic methodologies of utilizing a library of aminosugars can be a model for future studies of glycodiversification or glycorandomization.
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Pyranmycins, a Novel Class of Aminoglycosides with Improved Acid Stability: The SAR of d-Pyranoses on Ring III of Pyranmycin
TL;DR: The synthesis of a novel class of aminoglycosides, pyranmycins, is reported along with the structure activity relationship (SAR) of their antibacterial activity against Escherichia coli, which will lead to the future designs of p Pyranmycin against drug resistant bacteria.
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Synthesis and pharmacological activity of a potent inhibitor of the biosynthesis of the endocannabinoid 2-arachidonoylglycerol
Tiziana Bisogno,James J. Burston,Ravi Rai,Marco Allarà,Bijali Saha,Anu Mahadevan,Raj K. Razdan,Jenny L. Wiley,Vincenzo Di Marzo +8 more
TL;DR: Biosynthesis Inhibition: O‐5596, a new inhibitor of the biosynthesis of the endocannabinoid, 2‐arachidonoylglycerol, was synthesized and found to be potent and selective versus other proteins and enzymes of the Endocannabinoids system in vitro and active in vivo at reducing food intake in mice.
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Synthesis of trehalose-based compounds and their inhibitory activities against Mycobacterium smegmatis.
Jinhua Wang,Bryan Elchert,Yu Hui,Jon Y. Takemoto,Mekki F. Bensaci,John Wennergren,Huiwen Chang,Ravi Rai,Cheng-Wei Tom Chang +8 more
TL;DR: The synthesis of a library of trehalose-based compounds has been accomplished, and their activities against Mycobacterium smegmatis have been determined, and a preliminary structure-activity relationship (SAR) is reported.
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