Rashed Abdullah
St. John's University
11 Papers
164 Citations
Rashed Abdullah is an academic researcher from St. John's University. The author has contributed to research in topics: Neurodegeneration & Parkinson's disease. The author has an hindex of 8, co-authored 11 publications. Previous affiliations of Rashed Abdullah include Pfizer & Columbia University.
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Papers
•Journal Article
A Fully Human Monoclonal Antibody to the Insulin-Like Growth Factor I Receptor Blocks Ligand-Dependent Signaling and Inhibits Human Tumor Growth in Vivo
Douglas Burtrum,Zhenping Zhu,Dan Lu,Donna Marie Anderson,Marie Prewett,Daniel S. Pereira,Rajiv Bassi,Rashed Abdullah,Andrea T. Hooper,Henry Koo,Xenia Jimenez,Danielle P. Johnson,Robin Apblett,Paul Kussie,Peter Bohlen,Larry Witte,Daniel J. Hicklin,Dale L. Ludwig +17 more
TL;DR: Results demonstrate that A12 possesses strong antitumor activity in vitro and in vivo and may therefore be an effective therapeutic candidate for the treatment of cancers that are dependent on IGF-IR signaling for growth and survival.
Identification of a transiently exposed VE-cadherin epitope that allows for specific targeting of an antibody to the tumor neovasculature
Chad May,Jacqueline Doody,Jacqueline Doody,Rashed Abdullah,Rashed Abdullah,Paul J. Balderes,Paul J. Balderes,Xiaohong Xu,Xiaohong Xu,Chien Peter Chen,Chien Peter Chen,Zhenping Zhu,Zhenping Zhu,Lawrence Shapiro,Lawrence Shapiro,Paul Kussie,Paul Kussie,Daniel J. Hicklin,Daniel J. Hicklin,Fang Liao,Fang Liao,Peter Bohlen,Peter Bohlen +22 more
TL;DR: These findings establish the immediate N-terminal region of VE-cadherin as a novel target for inhibiting angiogenesis and demonstrates that conserved tryptophan residues in this sequence are required for Ve-c cadherin-mediated trans-adhesion.
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Parkinson's disease and age: The obvious but largely unexplored link.
Rashed Abdullah,Indranil Basak,Ketan S. Patil,Guido Alves,Jan Petter Larsen,Simon Geir Møller,Simon Geir Møller +6 more
TL;DR: In this review, some of the central proteins associated with Parkinson's disease are highlighted and how they may be linked to processes and factors associated with age.
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Alphavirus replicon particles encoding the fusion or attachment glycoproteins of respiratory syncytial virus elicit protective immune responses in BALB/c mice and functional serum antibodies in rhesus macaques.
Matthew B. Elliott,Tong Chen,Nicole B. Terio,Siew-Yen Chong,Rashed Abdullah,Amara Luckay,Michael A. Egan,Lee Anne C. Boutilier,Krista J. Melville,Robert A. Lerch,Deborah Long,John H. Eldridge,Christopher L. Parks,Stephen A. Udem,Gerald E. Hancock +14 more
TL;DR: The replicon-based platform represents a promising new strategy for vaccines against RSV and was protective against intranasal challenge with RSV.
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Neurovirulence and immunogenicity of attenuated recombinant vesicular stomatitis viruses in nonhuman primates.
David K. Clarke,Farooq Nasar,Siew Yen Chong,J. Erik Johnson,John W. Coleman,Margaret Lee,Susan E. Witko,Cheryl S. Kotash,Rashed Abdullah,Shakuntala Megati,Amara Luckay,Becky Nowak,Andrew A. Lackner,Roger E. Price,Peter B. Little,Narender K. Kalyan,Valerie Randolf,Ali Javadian,Timothy J. Zamb,Christopher L. Parks,Michael A. Egan,John H. Eldridge,Michael Hendry,Stephen A. Udem +23 more
TL;DR: These data demonstrate novel approaches to the rational attenuation of VSIV NV while retaining vector immunogenicity and have led to identification of an attenuated, replication-competent rVSIV vector that has successfully undergone its first clinical evaluation in humans.
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