Ramesh Vemuri
University of California, Los Angeles
5 Papers
13 Citations
Ramesh Vemuri is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Vesicle & Sodium-calcium exchanger. The author has an hindex of 5, co-authored 5 publications.
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Papers
Identification of the cardiac sarcolemmal Na+−Ca2+ exchanger using monoclonal antibodies
TL;DR: The generation of three stable murine hybridoma lines which secrete monoclonal antibodies (MAb's) to the exchanger provide strong support for the prevous association of Na+−Ca2+ exchange with these proteins.
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Protein methylation inhibits Na+-Ca2+ exchange activity in cardiac sarcolemmal vesicles.
TL;DR: It is verified that many membrane proteins, probably including the exchanger, become methylated, and inhibition of Na+-Ca2+ exchange was due to methylation of membrane protein and not to methylated phosphatidylethanolamine (PE) compounds.
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Phospholipid composition modulates the Na+-Ca2+ exchange activity of cardiac sarcolemma in reconstituted vesicles
TL;DR: The results indicate that optimal Na+-Ca2+ exchange activity requires the presence of certain anionic phospholipids, and that the mechanism of action of altered pH on the exchanger appears to be different from other interventions.
Influence of phospholipid fatty acyl composition on sarcolemmal and sarcoplasmic reticular cation transporters.
TL;DR: Using solubilization/reconstitution techniques, the dependence on membrane fatty acyl composition for all three transporters was identical, and the influence of membrane fatty Acyl composition on the activities of sarcolemmal and sarcoplasmic reticular transporators was investigated.
Effect of temperature on sodium-calcium exchange in sarcolemma from mammalian and amphibian hearts.
TL;DR: It is concluded that the lesser temperature sensitivity of the cardiac sarcolemmal Na(+)-Ca2+ exchanger of a poikilothermic species is at least partly an intrinsic property of the transport protein.