Ramamoorthy Senthilkumar
Council of Scientific and Industrial Research
4 Papers
58 Citations
Ramamoorthy Senthilkumar is an academic researcher from Council of Scientific and Industrial Research. The author has contributed to research in topics: Drosophila melanogaster & Drosophila Protein. The author has an hindex of 4, co-authored 4 publications. Previous affiliations of Ramamoorthy Senthilkumar include International Institute of Information Technology & International Institute of Information Technology, Hyderabad.
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Papers
Nuclear matrix proteome analysis of Drosophila melanogaster
TL;DR: A subset of NuMat proteins remains associated with the mitotic chromosomes, implicating their role in mitosis and possibly the epigenetic cellular memory, and NuMat proteome analysis provides tools and opens up ways to understand nuclear organization and function.
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Repeat performance: how do genome packaging and regulation depend on simple sequence repeats?
Ram Parikshan Kumar,Ramamoorthy Senthilkumar,Ramamoorthy Senthilkumar,Vipin Kumar Singh,Rakesh Mishra +4 more
TL;DR: It is proposed that repeats play a regulatory role by contributing to the packaging of the genome during cellular differentiation and function as common target sites for regulatory mechanisms involved in the packaging and dynamic compartmentalization of the chromatin into active and inactive regions during Cellular differentiation.
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Functional diversification of yeast telomere associated protein, Rif1, in higher eukaryotes.
TL;DR: Telomeres are maintained by retrotransposons in all Drosophila species and consequently, telomerase and many of the telomere associated protein homologues are absent, including Rap1, which is the binding partner of Rif1.
Novel motifs distinguish multiple homologues of Polycomb in vertebrates: expansion and diversification of the epigenetic toolkit
TL;DR: The analysis of the sequence of PC homologues in various organisms shows that PC is an ancient gene dating back to pre bilaterian origin that has not only been conserved but has also expanded during the evolution of complexity.