Ralph Simanek
Medical University of Vienna
23 Papers
88 Citations
Ralph Simanek is an academic researcher from Medical University of Vienna. The author has contributed to research in topics: Cancer & Prospective cohort study. The author has an hindex of 13, co-authored 22 publications.
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Papers
Prediction of venous thromboembolism in cancer patients
Cihan Ay,Daniela Dunkler,Christine Marosi,Alexandru-Laurentiu Chiriac,Rainer Vormittag,Ralph Simanek,Peter Quehenberger,Christoph C. Zielinski,Ingrid Pabinger +8 more
TL;DR: Clinical and standard laboratory parameters with addition of biomarkers enable prediction of VTE and allow identification of cancer patients at high or low risk of V TE.
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D-Dimer and Prothrombin Fragment 1 + 2 Predict Venous Thromboembolism in Patients With Cancer: Results From the Vienna Cancer and Thrombosis Study
Cihan Ay,Rainer Vormittag,Daniela Dunkler,Ralph Simanek,Alexandru-Laurentiu Chiriac,Johannes Drach,Peter Quehenberger,Oswald Wagner,Christoph C. Zielinski,Ingrid Pabinger +9 more
TL;DR: High D-dimer and F 1 + 2 levels independently predict occurrence of VTE in patients with cancer.
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High plasma levels of soluble P-selectin are predictive of venous thromboembolism in cancer patients: results from the Vienna Cancer and Thrombosis Study (CATS)
Cihan Ay,Ralph Simanek,Rainer Vormittag,Daniela Dunkler,Guelay Alguel,Silvia Koder,Gabriela Kornek,Christine Marosi,Oswald Wagner,Christoph C. Zielinski,Ingrid Pabinger +10 more
TL;DR: Elevated sP-selectin (cutoff level, 53.1 ng/mL, 75th percentile of study population) was a statistically significant risk factor for VTE after adjustment for age, sex, surgery, chemotherapy, and radiotherapy (hazard ratio, 2.6, 95% confidence interval, 1.4-4.9, P = .003).
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Prediction of Venous Thromboembolism in Patients With Cancer by Measuring Thrombin Generation: Results From the Vienna Cancer and Thrombosis Study
Cihan Ay,Daniela Dunkler,Ralph Simanek,Johannes Thaler,Silvia Koder,Christine Marosi,Christoph C. Zielinski,Ingrid Pabinger +7 more
TL;DR: Investigation of thrombin generation, a key process in hemostasis, as predictor of cancer-associated venous thromboembolism found it to help identify patients with cancer at high risk of VTE.
226
Venous thromboembolism--a manifestation of the metabolic syndrome.
Cihan Ay,Theres Tengler,Rainer Vormittag,Ralph Simanek,Wolfgang Dorda,Thomas Vukovich,Ingrid Pabinger +6 more
TL;DR: The metabolic syndrome may contribute to the development of V TE and is associated with a two-fold increased risk of VTE.
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