Ralph C. Ward
Medical University of South Carolina
30 Papers
76 Citations
Ralph C. Ward is an academic researcher from Medical University of South Carolina. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 4, co-authored 19 publications. Previous affiliations of Ralph C. Ward include United States Department of Veterans Affairs.
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Papers
Methods for Analysis of Pre-Post Data in Clinical Research: A Comparison of Five Common Methods
Nathaniel O'Connell,Lin Dai,Yunyun Jiang,Jaime L. Speiser,Ralph C. Ward,Wei Wei,Rachel Carroll,Mulugeta Gebregziabher +7 more
TL;DR: The results demonstrate that each method leads to unbiased treatment effect estimates, and based on precision of estimates, 95% coverage probability, and power, ANCOVA modeling of either change scores or post-treatment score as the outcome, prove to be the most effective.
Genes associated with SLE are targets of recent positive selection.
TL;DR: This study is the first to evaluate and report that several SLE-associated regions show signs of positive natural selection, providing corroborating evidence in support of recent positive selection as one mechanism underlying the elevated population frequency of SLE risk loci and supports future research that integrates signals of natural selection to help identify functional SLErisk alleles.
Diffusion MRI detects longitudinal white matter changes in the 3xTg-AD mouse model of Alzheimer's disease.
Xingju Nie,Maria F. Falangola,Ralph C. Ward,Emilie T. McKinnon,Joseph A. Helpern,Paul J. Nietert,Jens H. Jensen +6 more
TL;DR: It is demonstrated that dMRI can detect microstructural changes in white matter for the 3xTg-AD mouse model due to aging and/or progression of pathology, depending strongly on the diffusion parameter and anatomical region.
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Airflow limitation and mortality during cancer screening in the National Lung Screening Trial: why quantifying airflow limitation matters
TL;DR: In this paper , the authors examined the relationship between the presence and severity of advanced airflow limitation (AL) and screening outcomes and found that severe AL was not associated with any apparent reduction in lung cancer mortality following screening.
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Diffusion MRI detects early brain microstructure abnormalities in 2-month-old 3×Tg-AD mice.
Maria F. Falangola,Xingju Nie,Ralph C. Ward,Emilie T. McKinnon,Siddhartha Dhiman,Paul J. Nietert,Joseph A. Helpern,Jens H. Jensen +7 more
TL;DR: Results indicate, for the first time, dMRI changes associated with myelin abnormalities in young 3×Tg-AD mice, before they develop AD pathology.
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