Ralf P. Brandes
Goethe University Frankfurt
306 Papers
2.4K Citations
Ralf P. Brandes is an academic researcher from Goethe University Frankfurt. The author has contributed to research in topics: NADPH oxidase & Biology. The author has an hindex of 77, co-authored 271 publications. Previous affiliations of Ralf P. Brandes include University of California, San Francisco & University of Würzburg.
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Papers
The Polarity Protein Scrib Is Essential for Directed Endothelial Cell Migration
U. Ruth Michaelis,Emmanouil Chavakis,Christoph Kruse,Benno Jungblut,David Kaluza,Katalin Wandzioch,Yosif Manavski,Heinrich Heide,Marie-Josée Santoni,Michael Potente,Johannes A. Eble,Jean-Paul Borg,Ralf P. Brandes +12 more
TL;DR: Scrib is a novel regulator of integrin &agr;5 turnover and sorting, which is required for oriented cell migration and sprouting angiogenesis, and downregulation of Scrib function in Tg(kdrl:EGFP)s843 transgenic zebrafish embryos delayed theAngiogenesis of intersegmental vessels.
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Hypoxia-Dependent Reactive Oxygen Species Signaling in the Pulmonary Circulation: Focus on Ion Channels
TL;DR: Current knowledge on hypoxia-induced ROS-mediated ion channel signaling in the pulmonary circulation is summarized and a better understanding of redox protein modifications is needed to determine the complexity of ion channel redox regulation.
Investigation of factors affecting fluorometric quantitation of cytosolic [Ca2+] in perfused hearts.
TL;DR: These studies suggest conditions in which experimental artifacts could be minimized to allow reliable quantitation of [Ca2+]c in intact perfused hearts using Indo-1 fluorometry.
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Inhibition of the soluble epoxide hydrolase attenuates monocrotaline-induced pulmonary hypertension in rats
Marc Revermann,Eduardo Barbosa-Sicard,Eva Dony,Ralph T. Schermuly,Christophe Morisseau,Gerd Geisslinger,Ingrid Fleming,Bruce D. Hammock,Ralf P. Brandes +8 more
TL;DR: In this paper, sEH inhibition was achieved using 12-(3-adamantan-1-yl-ureido)-dodecanoic acid (25 mg/l) and cis- 4-[4-(3]-4]-hexyloxy]-benzoic acid, administered via drinking water starting 3 days prior to monocrotaline injection (60 mg/kg).
Long non-coding RNAs: novel regulators of cellular physiology and function.
TL;DR: Long non-coding RNAs (LncRNAs) as discussed by the authors are defined as transcripts longer than 200 nucleotides that do not encode a peptide, and they are considered as "junk" RNA produced by aberrant DNA transcription.
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