Rainer Bischoff
University of Groningen
347 Papers
3K Citations
Rainer Bischoff is an academic researcher from University of Groningen. The author has contributed to research in topics: Chemistry & Mass spectrometry. The author has an hindex of 54, co-authored 327 publications. Previous affiliations of Rainer Bischoff include Centre national de la recherche scientifique & Max Planck Society.
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Papers
Physiology and pathophysiology of matrix metalloproteases
Theo Klein,Rainer Bischoff +1 more
TL;DR: An overview of 23 members of the human MMP family is given and functions, linkages to disease and structural and mechanistic features are described.
Recommendations for Biomarker Identification and Qualification in Clinical Proteomics
Harald Mischak,Guenter Allmaier,Rolf Apweiler,Teresa K. Attwood,Marc Baumann,Ariela Benigni,Samuel E. Bennett,Rainer Bischoff,Erik Bongcam-Rudloff,Giovambattista Capasso,Joshua J. Coon,Patrick C. D'Haese,Anna F. Dominiczak,Mohammed Dakna,Hassan Dihazi,Jochen H. H. Ehrich,Patricia Fernández-Llama,Danilo Fliser,Jørgen Frøkiær,Jérôme Garin,Mark Girolami,William S. Hancock,Marion Haubitz,Denis F. Hochstrasser,Rury R. Holman,John P. A. Ioannidis,Joachim Jankowski,Bruce A. Julian,Jon B. Klein,Walter Kolch,Theo M. Luider,Ziad A. Massy,William B. Mattes,Franck Molina,Bernard Monsarrat,Jan Novak,Karlheinz Peter,Peter Rossing,Marta Sanchez-Carbayo,Joost P. Schanstra,O. John Semmes,Goce Spasovski,Dan Theodorescu,Visith Thongboonkerd,Raymond Vanholder,Timothy D. Veenstra,Eva M. Weissinger,Tadashi Yamamoto,Antonia Vlahou +48 more
TL;DR: It is asserted that successful studies generally use suitable statistical approaches for biomarker definition and confirm results in independent test sets and a brief set of practical and feasible recommendations are described for investigators to properly identify and qualify proteomic biomarkers, which could also be used as reporting requirements.
An automated on-line multidimensional HPLC system for protein and peptide mapping with integrated sample preparation.
TL;DR: The system was applied to protein mapping of biological samples of human hemofiltrate as well as of cell lysates originating from a human fetal fibroblast cell line, demonstrating it to be a viable alternative to 2D gel electrophoresis for mapping peptides and small proteins.
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Cytoplasmic p21 expression levels determine cisplatin resistance in human testicular cancer
Roelof Koster,Alessandra di Pietro,Hetty Timmer-Bosscha,Johan H. Gibcus,Anke van den Berg,Albert J. H. Suurmeijer,Rainer Bischoff,Jourik A. Gietema,Steven de Jong +8 more
TL;DR: Targeting cytoplasmic p21, including by modulation of the Oct4/miR-106b/p21 pathway, may offer new strategies for the treatment of chemoresistant testicular and other types of cancer.
Receptor-ligand binding assays: technologies and applications.
TL;DR: Applications of receptor-ligand binding assays described in this review will relate to screening and the quantification of pharmaceuticals in biological matrices.
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