Rabiah Fardoos
University of Copenhagen
6 Papers
23 Citations
Rabiah Fardoos is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Medicine & Immunology. The author has an hindex of 2, co-authored 4 publications.
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Papers
Single-cell profiling of environmental enteropathy reveals signatures of epithelial remodeling and immune activation
Conner Kummerlowe,Simutanyi Mwakamui,Travis K. Hughes,Nolawit Mulugeta,Victor Mudenda,Ellen Besa,Kanekwa Zyambo,Jessica E.S. Shay,Ira Fleming,Marko Vukovic,Benjamin Doran,Toby Aicher,Marc H. Wadsworth,Juliet Bramante,Amiko M. Uchida,Rabiah Fardoos,Osaretin E. Asowata,N. Herbert,Ömer H. Yilmaz,Henrik N. Kløverpris,John J. Garber,Jose Ordovas-Montanes,Zev J. Gartner,Thomas Dr. Wallach,Alex K. Shalek,Paul J. Kelly +25 more
TL;DR: The cellular and molecular correlates of EE are mapped by performing high-throughput, single-cell RNA-sequencing on 33 small intestinal biopsies from 11 adults with EE in Lusaka, Zambia, six adults without EE in Boston, United States, and two adults in Durban, South Africa, which are complemented with published data from three additional individuals from the same clinical site.
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Irreversible depletion of intestinal CD4+ T-cells is associated with T-cell activation during chronic HIV infection
Osaretin E. Asowata,Alveera Singh,Abigail Ngoepe,Nicholas Herbert,Rabiah Fardoos,Kavidha Reddy,Yenzekile Zungu,Faith Nene,Ntombifuthi Mthabela,Dirhona Ramjit,Farina Karim,Katya Govender,Thumbi Ndung'u,J Zachary Porterfield,John H. Adamson,Fusi G. Madela,Vukani T. Manzini,Frank Anderson,Alasdair Leslie,Alasdair Leslie,Henrik N. Kløverpris +20 more
TL;DR: In this article, a large cohort recruited from high HIV endemic areas in South Africa and found that people living with HIV (PLWH) presented at a younger age for investigation in the GI clinic.
Innate Lymphoid Cell Activation and Sustained Depletion in Blood and Tissue of Children Infected with HIV from Birth Despite Antiretroviral Therapy
Alveera Singh,Samuel W. Kazer,J Roider,Kami C. Krista,Kami C. Krista,Kami C. Krista,Jane Millar,Osaretin E. Asowata,Abigail Ngoepe,Duran Ramsuran,Rabiah Fardoos,Amanda Ardain,Maximilian Muenchhoff,Warren Kuhn,Farina Karim,Thumbi Ndung'u,Alex K. Shalek,Alex K. Shalek,Alex K. Shalek,Philip J. R. Goulder,Alasdair Leslie,Henrik N. Kløverpris +21 more
TL;DR: An important and ongoing role is suggested for ILCs in lymphoid tissue of HIV-infected children from birth, where persistent depletion and sustained transcriptional activity are likely to have long-term immune consequences that merit further investigation.
13
Immunodominant cytomegalovirus-specific CD8+ T-cell responses in sub-Saharan African populations.
Amna Malik,Emily Adland,Leana Laker,Henrik N. Kløverpris,Henrik N. Kløverpris,Rabiah Fardoos,Julia Roider,Mai Charlotte Krogh Severinsen,Fabian Chen,Lynn Riddell,Anne Edwards,Søren Buus,Pieter Jooste,Philippa C Matthews,Philip J. R. Goulder +14 more
TL;DR: These predicted novel CMV-specific CD8+ T-cell epitopes identified in an African cohort will facilitate future analyses of immune responses in African populations where CMV infection is almost universal during infancy.
HIV infection drives interferon signaling within intestinal SARS-CoV-2 target cells.
Rabiah Fardoos,Osaretin E. Asowata,Nicholas Herbert,Sarah K. Nyquist,Yenzekile Zungu,Alveera Singh,Abigail Ngoepe,Ian M. Mbano,Ntombifuthi Mthabela,Dirhona Ramjit,Farina Karim,Warren Kuhn,Fusi G. Madela,Vukani T. Manzini,Frank Anderson,Bonnie Berger,Tune H. Pers,Alex K. Shalek,Alasdair Leslie,Henrik N. Kløverpris +19 more
TL;DR: In this paper, single-cell transcriptional profiles and SARS-CoV-2 entry receptor expression across lymphoid and mucosal human tissue from chronically HIV-infected individuals and uninfected controls were analyzed.