In this study quantitative techniques have been applied to smears collected from the buccal mucosa and floor of the mouth. The results display an encouraging success rate for identifying premalignant and malignant lesions. 'Intrapatient' normal smears provide a satisfactory control for comparison with pathological smears. Early results indicate that quantitative cytology could be of great value for monitoring and follow-up of suspicious lesions and provide an excellent additional diagnostic test for detecting early oral malignancy.

https://journals.sagepub.com/doi/pdf/10.1177/014107688808100905

Quantitative exfoliative cytology of abnormal oral mucosal smears

https://acsjournals.onlinelibrary.wiley.com/doi/pdf/10.1002/1097-0142%28196211/12%2915%3A6%3C1119%3A%3AAID-CNCR2820150605%3E3.0.CO%3B2-A

Cytological screening for early mouth cancer. Interim report of the veterans administration co‐operative study of oral exfoliative cytology

Background Early detection of oral cancers is not easy, because oral precancerous lesions and early oral cancers can mimic many benign conditions in the mouth, leading to delays in diagnosis and treatment There is a need to emphasize the early diagnosis of oral cancers in order to reduce the unacceptably high morbidity and mortality Methods A survey regarding oral exfoliative cytology was completed by 132 dentists in Virginia who were randomly chosen from a mailing list Results Less than half of the dentists (417%) had been taught how to obtain a cytologic smear, and only 260% knew the clinical indications for doing so Only 92% of the dentists had ever obtained a cytologic smear in private practice Of the 13 dentists in the survey who had done so, 12 had been trained in the technique Interest in learning the cytologic technique and getting the needed supplies was indicated by 792% of the dentists Conclusions Diagnostic aids in the evaluation of oral mucosal lesions can serve an imp

The use of exfoliative cytology for the early diagnosis of oral cancers: is there a role for it in education and private practice?

Physicians ond dentists must accept responsibility for finding oral cancer, examination technics must preclude missing small lesions, abnormalities must be recognized, and effective action must be taken on what is observed.

https://jada.ada.org/article/S0002-8177(67)45019-3/pdf

Oral cancer prevention and detection

Correlated study of oral cytology and histopathology: Report on 2,052 oral lesions

Oral smears in the diagnosis of carcinoma and premalignant lesions.

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Oral smears in the diagnosis of carcinoma and premalignant lesions.