R. Oliver
University of Miami
9 Papers
55 Citations
R. Oliver is an academic researcher from University of Miami. The author has contributed to research in topics: Islet & Transplantation. The author has an hindex of 5, co-authored 9 publications.
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Papers
Transplantation of allogeneic islets of Langerhans in the rat liver: effects of macrophage depletion on graft survival and microenvironment activation.
Rita Bottino,L. Fernandez,L. Fernandez,Camillo Ricordi,R. Lehmann,Min Fu Tsan,R. Oliver,Luca Inverardi +7 more
TL;DR: Evidence is provided to support the concept that macrophages play a key role in early inflammatory events known to adversely affect islet engraftment and suggest that manipulation of nonspecific immune activation by inhibition of macrophage function may facilitate hepatic engraftedment of islet allografts.
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Endotoxin-mediated delayed islet graft function is associated with increased intra-islet cytokine production and islet cell apoptosis.
Thierry Berney,R. D. Molano,Pierre Cattan,Antonello Pileggi,Caterina Vizzardelli,R. Oliver,Camillo Ricordi,Luca Inverardi +7 more
TL;DR: It is proposed that endotoxin contamination is the primum movens of a chain of events that involves intra-islet cytokine production and release and islet cell apoptosis, and endotoxin contaminated reagents can ultimately lead to primary nonfunction in vivo.
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Prolonged Islet Allograft Survival in Diabetic NOD Mice by Targeting CD45RB and CD154
R. Damaris Molano,Antonello Pileggi,Thierry Berney,Raffaella Poggioli,E. Zahr,R. Oliver,Camillo Ricordi,David M. Rothstein,Giacomo Basadonna,Luca Inverardi +9 more
TL;DR: Data show that nondiabetogenic regimens of immunomodulation can lead to prolonged islet allograft survival in the challenging NOD mouse model.
Long-term islet allograft survival in nonobese diabetic mice treated with tacrolimus, rapamycin, and anti-interleukin-2 antibody.
R. Damaris Molano,Antonello Pileggi,Thierry Berney,Raffaella Poggioli,E. Zahr,R. Oliver,Thomas R. Malek,Camillo Ricordi,Luca Inverardi +8 more
TL;DR: The dramatic prolongation of graft survival observed in the authors’ study seems to validate the NOD mouse as a meaningful model for the study of therapeutic interventions for the prevention of islet graft loss.
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