R Mitteregger
Danube University Krems
8 Papers
96 Citations
R Mitteregger is an academic researcher from Danube University Krems. The author has contributed to research in topics: Tumor necrosis factor alpha & Peripheral blood mononuclear cell. The author has an hindex of 6, co-authored 8 publications.
Chat about Author
Papers
Rotary cell culture system (RCCS): a new method for cultivating hepatocytes on microcarriers.
TL;DR: It is concluded that this new RCCS is an excellent technology for culturing HepG2 cells on Cytodex 3 mcs and enables to culture anchorage dependent cells to high densities in a short period.
62
Can sterile and pyrogen-free on-line substitution fluid be routinely delivered? A multicentric study on the microbiological safety of on-line haemodiafiltration.
Lajos Vaslaki,A. Karátson,P. Vörös,Lajos Major,F. Pethö,Erzsébet Ladányi,Christoph Weber,R Mitteregger,Dieter Falkenhagen +8 more
TL;DR: On-line HDF treatment can routinely be provided with ultra-pure dialysis fluids and sterile substitution fluids at pyrogen-free levels and can be considered microbiologically safe, according to a redundant safety mode of the on-line system by a second filtration step.
Novel online infusate-assisted dialysis system performs microbiologically safely.
TL;DR: The present online system is comprehensive, operates user-friendly, and provides microbiologically safe infusate in large quantities, and both patients and dialysis staff will benefit from improved dialysis therapy and reduced treatment-related labor burden, respectively.
26
In Vitro Cell Culture Systems as the Basis for an Extracorporeal Blood Purification Strategy In Multiorgan Failure Treatment
R Mitteregger,Adrienne White,Christoph Weber,Eva Rossmanith,Thomas Mohr,Michael Micksche,Dieter Falkenhagen +6 more
TL;DR: Test the effectiveness of endotoxin and cytokine removal to blunt cellular response and cell culture models are suitable to simulate cell interaction in MOF, showing that after the initial addition of endotoxins, the activation of monocytes can be stopped within 120 min by added endotoxin adsorbents.
12
Comparison of specific adsorbents for tumor necrosis factor-alpha and therapeutic anti-tumor necrosis factor-alpha antibodies: an in vitro sepsis model.
TL;DR: Adsorption techniques using specific adsorbents, possibly used in MDS (Microspheres-Based Detoxification System), are efficient in specific reduction of TNF-α and pathophysiological consequences, since monocyte adhesion at activated HUVECs was shown to be reduced.
6