R. Leonardi
University of Catania
66 Papers
311 Citations
R. Leonardi is an academic researcher from University of Catania. The author has contributed to research in topics: Computer science & Medicine. The author has an hindex of 19, co-authored 43 publications.
Chat about Author
Papers
Survivin, a potential early predictor of tumor progression in the oral mucosa
Lorenzo Lo Muzio,Giuseppe Pannone,R. Leonardi,Stefania Staibano,Michele D. Mignogna,G. De Rosa,Yasusei Kudo,Takashi Takata,Dario C. Altieri +8 more
TL;DR: High expression of cytoplasmic/nuclear survivin is an early event during oral carcinogenesis and may provide a useful tool for the identification of precancerous lesions at higher risk of progression into invasive carcinoma.
109
An ex vivo study on immunohistochemical localization of MMP-7 and MMP-9 in temporomandibular joint discs with internal derangement.
TL;DR: MMP-7 and MMP-9 upregulation in discs from patients with TMJ ID demonstrates their involvement in disc damage in this disorder and could help identify ways to curb MMP overproduction without affecting their tissue remodelling action.
HSP 27 as possible prognostic factor in patients with oral squamous cell carcinoma.
Lo Muzio L,R. Leonardi,Maria Addolorata Mariggiò,Mignogna,Corrado Rubini,A. Vinella,Giuseppe Pannone,Luca Giannetti,Rosario Serpico,Testa Nf,De Rosa G,Stefania Staibano +11 more
TL;DR: It is suggested that HSP27 expression may be useful in order to identify cases of oral squamous cell carcinoma with more aggressive and invasive phenotype providing novel diagnostic and prognostic information on individual patient survival with oral cancers.
Altered joint tribology in osteoarthritis: Reduced lubricin synthesis due to the inflammatory process. New horizons for therapeutic approaches
TL;DR: In this article, a review aimed to consolidate the current evidence that implicates the inflammatory process in the attenuation of synovial lubrication and joint tissue homeostasis in OA.
44
Expression of vascular endothelial growth factor in human dysfunctional temporomandibular joint discs
TL;DR: Investigation of the expression of vascular endothelial growth factor (VEGF), a multifunctional cytokine that contributes to angiogenesis, in human TMJ discs found VEGF expression by disc chondrocyte-like cells might reflect the action of the cytokine as an inducer ofAngiogenesis and as an autocrine signal for cells of the chondrogenic lineage.
44