R. Jerome Nickles
University of Wisconsin-Madison
15 Papers
106 Citations
R. Jerome Nickles is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Dopamine & Beam (structure). The author has an hindex of 9, co-authored 15 publications.
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Papers
PET/CT following intensity-modulated radiation therapy for primary lung tumor in a dog.
TL;DR: Fusion of functional imaging with anatomic imaging is a useful tool, particularly in the field of oncology, with the potential for PET markers that delineate tumor from normal or reactive tissue, and potential or actual response to therapy.
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6-FluoroDOPA metabolism in rat striatum: time course of extracellular metabolites
TL;DR: The pharmacokinetics of individual FDOPA metabolites in extracellular space in the striata of anesthetized rats was investigated using in vivo microdialysis and whole striatal tissue confirmed the intraneuronal localization of fluorodopamine most likely stored in vesicles.
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Nonuniform cardiac denervation observed by 11C-meta-hydroxyephedrine PET in 6-OHDA-treated monkeys
Valerie Joers,Kailie Seneczko,Nichole C. Goecks,Timothy J. Kamp,Timothy A. Hacker,Kevin Brunner,Jonathan W. Engle,Todd E. Barnhart,R. Jerome Nickles,James E. Holden,Marina E. Emborg +10 more
TL;DR: It is demonstrated that systemic injection of 6-hydroxydopamine in nonhuman primates creates a nonuniform but reproducible pattern of cardiac denervation as well as a persistent loss of circulating catecholamines, supporting the use of this method to further develop a monkey model of cardiac dysautonomia.
[18F]Fluoro-β-fluoromethylene-m-tyrosine analogs, potential PET agents for presynaptic dopamine terminals : synthesis and spectroscopic characterization
TL;DR: In this paper, an F-labeled (E )-β- fluoromethylene -DL -m- tyrosine (FMMT) was prepared by the direct reaction of FMMT with [18F]acetylhypofluorite (AcOF) resulting into three product isomers.
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A theoretical description of the beam induced heating of accelerator target foils
JR Votaw,R. Jerome Nickles +1 more
TL;DR: In this article, a nonlinear differential equation is solved by the method of successive approximations to determine a temperature distribution that is proven to converge arbitrarily close to the exact solution, and an upper limit is given for the maximum error in the distribution after a finite number of iterations.
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