Quitterie Venot
French Institute of Health and Medical Research
8 Papers
7 Citations
Quitterie Venot is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 2, co-authored 5 publications. Previous affiliations of Quitterie Venot include Paris Descartes University.
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Papers
Targeted therapy in patients with PIK3CA-related overgrowth syndrome
Quitterie Venot,Thomas Blanc,Thomas Blanc,Thomas Blanc,Smail Hadj Rabia,Smail Hadj Rabia,Laureline Berteloot,Sophia Ladraa,J P Duong,J P Duong,Estelle Blanc,Simon C. Johnson,Clément Hoguin,Olivia Boccara,Sabine Sarnacki,Sabine Sarnacki,Nathalie Boddaert,Nathalie Boddaert,Stéphanie Pannier,Stéphanie Pannier,Frank Martinez,Sato Magassa,Junna Yamaguchi,Bertrand Knebelmann,Bertrand Knebelmann,Bertrand Knebelmann,Pierre Merville,Nicolas Grenier,Dominique Joly,Dominique Joly,Dominique Joly,Valérie Cormier-Daire,Valérie Cormier-Daire,Caroline Michot,Caroline Michot,Christine Bole-Feysot,Arnaud Picard,Arnaud Picard,Véronique Soupre,Stanislas Lyonnet,Stanislas Lyonnet,Jérémy Sadoine,Lotfi Slimani,Catherine Chaussain,Cécile Laroche-Raynaud,Laurent Guibaud,Christine Broissand,Jeanne Amiel,Jeanne Amiel,Christophe Legendre,Christophe Legendre,Christophe Legendre,Fabiola Terzi,Fabiola Terzi,Guillaume Canaud,Guillaume Canaud,Guillaume Canaud +56 more
TL;DR: This study provides the first direct evidence supporting PIK3CA inhibition as a promising therapeutic strategy in patients with PROS, by reversing symptoms in a mouse model of PROS/CLOVES syndrome, which results from gain-of-function mutations in PI3KCA.
476
PIK3CA gain-of-function mutation in adipose tissue induces metabolic reprogramming with Warburg-like effect and severe endocrine disruption
Sophia Ladraa,Lola Zerbib,Charles Bayard,A. Fraissenon,Quitterie Venot,Gabriel Morin,Alexandre P. Garneau,Pierre Isnard,Célia Chapelle,Clément Hoguin,Sylvie Fraitag,J P Duong,Laurent Guibaud,Alix Besançon,Sophie Kaltenbach,Patrick Villarese,Vahid Asnafi,Christine Broissand,Nicolas Goudin,Michael Dussiot,Ivan Nemazanyy,Thomas Viel,Gwennhael Autret,Céline Cruciani-Guglielmacci,Jessica Denom,Julie Bruneau,Bertrand Tavitian,Christophe Legendre,Julien Dairou,Jean-Marc Lacorte,Pacifique Lévy,Mario Pende,Michael Pollak,Guillaume Canaud +33 more
TL;DR: In this paper , a mouse model of PIK3CA-related adipose tissue overgrowth was created to recapitulate patient phenotype and the mouse phenotype was mainly driven through AKT2.
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PIK3CA-related overgrowth spectrum: animal model and drug discovery.
Quitterie Venot,Guillaume Canaud +1 more
TL;DR: A review on PIK3CA related overgrowth syndromes (PROS) is presented in this paper, where the authors summarize the currently available animal models and new treatments undergoing development.
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Les syndromes de surcroissance segmentaire et les stratégies thérapeutiques
Quitterie Venot,Guillaume Canaud +1 more
TL;DR: Cette revue detaille les differents syndromes de surcroissance segmentaire ainsi que les voies moleculaires impliquees and the options therapeutiques envisageables.
Respective roles of Pik3ca mutations and cyproterone acetate impregnation in mouse meningioma tumorigenesis.
Pierre-Cyril Comes,Tuan Le Van,Suzanne Tran,Solène Huard,Samiya Abi-Jaoude,Quitterie Venot,Pauline Marijon,Julien Boetto,Franck Bielle,Yohan Ducos,Yumiko Teranishi,Michel Kalamarides,Matthieu Peyre +12 more
TL;DR: In this article , the effect of PIK3CA mutations in postnatal meningeal cells is shown to not only promote meningioma formation but also tumor progression in mice, while hormone impregnation, whether alone or in association with Pik3CA and Nf2 mutations, fails to induce meningIoma tumorigenesis while promoting breast tumor formation.
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