Quinten Patterson
University of Texas Southwestern Medical Center
5 Papers
19 Citations
Quinten Patterson is an academic researcher from University of Texas Southwestern Medical Center. The author has contributed to research in topics: Renal function & Lymphatic system. The author has an hindex of 2, co-authored 4 publications.
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Papers
Novel truncating mutations in CTNND1 cause a dominant craniofacial and cardiac syndrome
Reham Alharatani,Athina Vervari,Ana Beleza-Meireles,Ana Beleza-Meireles,Weizhen Ji,Emily K Mis,Quinten Patterson,John N. Griffin,John N. Griffin,Nabina Bhujel,Caitlin A. Chang,Abhijit Dixit,Monica Konstantino,Chris Healy,Sumayyah Hannan,Natsuko Neo,Natsuko Neo,Alex Cash,Dong Li,Elizabeth J. Bhoj,Elaine H. Zackai,Ruth Cleaver,Diana Baralle,Meriel McEntagart,Ruth Newbury-Ecob,Richard H Scott,Jane A. Hurst,Ping Yee Billie Au,Marie Therese Hosey,Mustafa K. Khokha,Denise K. Marciano,Saquib A. Lakhani,Karen J. Liu +32 more
TL;DR: It is proposed that CTNND1 variants have a wider developmental role than previously described and that variations in this gene underlie not only cleft palate and BCD but may be expanded to a broader velocardiofacial-like syndrome.
Heterozygous Mutation of Vegfr3 Reduces Renal Lymphatics without Renal Dysfunction.
Hao Liu,Chitkale Hiremath,Quinten Patterson,Saumya Vora,Zhiguo Shang,Andrew R. Jamieson,Reto Fiolka,Kevin M. Dean,Michael T. Dellinger,Denise K. Marciano +9 more
TL;DR: In this paper, a mouse model containing a missense mutation in Vegfr3 (dubbed Chy) that abrogates its kinase ability was used to characterize renal lymphatics using tissue clearing, light-sheet microscopy, and computational analyses.
17
Novel truncating mutations in CTNND1 cause a dominant craniofacial and cardiac syndrome
Reham Alharatani,Athina Vervari,Ana Beleza-Meireles,Ana Beleza-Meireles,Weizhen Ji,Emily K Mis,Quinten Patterson,John N. Griffin,Nabina Bhujel,Caitlin A. Chang,Abhijit Dixit,Monica Konstantino,Chris Healy,Sumayyah Hannan,Natsuko Neo,Alex Cash,Dong Li,Elizabeth J. Bhoj,Elaine H. Zackai,Ruth Cleaver,Diana Baralle,Meriel McEntagart,Ruth Newbury-Ecob,Richard H Scott,Jane A. Hurst,Ping Yee Billie Au,Marie Therese Hosey,Denise K. Marciano,Mustafa K. Khokha,Saquib A. Lakhani,Karen J. Liu +30 more
TL;DR: It is proposed that CTNND1 variants have a wider developmental role than previously described, and that variations in this gene underlie not only cleft palate and BCD but may be expanded to a broader velocardiofacial-like syndrome.
14
Rap1 regulates lumen continuity via Afadin in renal epithelia.
Chitkale Hiremath,Lei Gao,Quinten Patterson,Haley Rose Barlow,Ondine Cleaver,Denise K. Marciano +5 more
TL;DR: In this article , the role of the small GTPase Rap1 in renal tubule formation and morphogenesis was examined, and it was shown that Rap1 is required for correct localization of Afadin to adherens junctions both in vitro and in vivo.
2
Heterozygous mutation of Vegfr3 decreases renal lymphatics but is dispensable for renal function
Hao Liu,Chitkale Hiremath,Quinten Patterson,Saumya Vora,Zhiguo Shang,Andrew R. Jamieson,Reto Fiolka,Kevin M. Dean,Michael T. Dellinger,Denise K. Marciano +9 more
TL;DR: In this article, a combination of tissue clearing, light-sheet microscopy and computational analyses was used to characterize renal lymphatics using a mixture of protein expression and histology data, and it was shown that Vegfr3 is required for development of kidney lymphatics.