Qixing Li
Southern Medical University
5 Papers
Qixing Li is an academic researcher from Southern Medical University. The author has contributed to research in topics: Antibody & Epitope. The author has an hindex of 1, co-authored 1 publications.
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Papers
Rheumatoid arthritis sera antibodies to citrullinated collagen type II bind to joint cartilage
Qixing Li,Yanpeng Li,Bibo Liang,Rui-long Xu,Bingze Xu,Erik Lönnblom,Hui Feng,Jing'an Bai,Roma Stawikowska,Changrong Ge,Aiping Lu,Gregg B. Fields,Lianbo Xiao,Rikard Holmdahl +13 more
TL;DR: In this paper , the occurrence and frequency of anti-citrullinated protein antibodies (ACPA) to cyclic citrullated type II collagen (COL2) epitope with a capacity to bind joint cartilage was investigated.
Pathogenic antibody response to glucose-6-phosphate isomerase targets a modified epitope uniquely exposed on joint cartilage
Taotao Li,Chang-hui Ge,Alexander Krämer,Outi Sareila,Monica Leu Agelii,Linda Johansson,Kristina Forslind,Erik Lönnblom,Min Yang,Bingze Xu,Qixing Li,Lei Cheng,Göran Bergström,Gonzalo Fernandez,Alf Kastbom,Solbritt Rantapää-Dahlqvist,Inger Gjertsson,Rikard Holmdahl +17 more
TL;DR: In this article , the authors identified the major pathogenic B cell epitope of the RA-associated autoantigen GPI, at position 293-307, exposed only on structurally modified GPI on the cartilage surface.
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The systemic lupus erythematosus-associated NCF190H allele synergizes with viral infection to cause mouse lupus but also limits virus spread
Yanpeng Li,Ana Coelho,Zhilei Li,Malin Alsved,Qixing Li,Jing Xu,Kutty Selva Nandakumar,Jakob Löndahl,Rikard Holmdahl +8 more
TL;DR: A systemic lupus erythematosus-associated SNP, NCF190H, synergizes with murine norovirus infection to induce lupus symptoms in mice, including glomerulonephritis and arthritis, by upregulating interferon and toll-like receptor signaling pathways.
Targeted inhibition of ATP5B gene prevents bone erosion in collagen-induced arthritis by inhibiting osteoclastogenesis.
Yanting Xu,Huijing Tan,Kaifei Liu,Cailing Wen,Caixia Pang,Haiqian Liu,Rui Xu,Qixing Li,Chonghua He,Kutty Selva Nandakumar,Chun Zhou +10 more
TL;DR: In this paper, the authors investigated the contribution of ATP5B in osteoclast differentiation and joint destruction, and suggested it as a potential therapeutic target for protecting bones in RA.
A subset of type-II collagen-binding antibodies prevents experimental arthritis by inhibiting FCGR3 signaling in neutrophils
Zhongwei Xu,Bingze Xu,Susanna L Lundström,A. Moreno-Giró,Danxia Zhao,Myriam Martin,Erik Lönnblom,Qixing Li,Alexander Krämer,Chang-hui Ge,Lei Cheng,Bibo Liang,Dongmei R Tong,Roma Stawikowska,Anna M. Blom,Gregg B Fields,Roman A. Zubarev,Rikard Holmdahl +17 more
TL;DR: It is concluded that R69-4 abrogates autoantibody-mediated arthritis mainly by hindering FCGR3 signaling, highlighting its potential clinical utility in acute RA.