Qiuping He
Chinese Academy of Sciences
10 Papers
12 Citations
Qiuping He is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Stem cell & Haematopoiesis. The author has an hindex of 7, co-authored 10 publications.
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Papers
Inflammatory signaling regulates hematopoietic stem and progenitor cell emergence in vertebrates
TL;DR: It is demonstrated that in both zebrafish and mouse embryos, inflammatory signaling is necessary and sufficient for HSPC emergence, in the absence of infection or pathological inflammation.
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G protein-coupled receptor 183 facilitates endothelial-to-hematopoietic transition via Notch1 inhibition
Panpan Zhang,Qiuping He,Dongbo Chen,Weixiao Liu,Lu Wang,Chunxia Zhang,Dongyuan Ma,Wei Li,Bing Liu,Feng Liu +9 more
TL;DR: It is shown that G protein-coupled receptor 183 (Gpr183) signaling serves as an indispensable switch for HSPC emergence by repressing Notch signaling before the onset of EHT, providing an attractive strategy for enhancing the in vitro generation of functional HSPCs.
BLOS2 negatively regulates Notch signaling during neural and hematopoietic stem and progenitor cell development
TL;DR: It is suggested that BLOS2 is a novel negative player in regulating Notch signaling through lysosomal trafficking to control multiple stem and progenitor cell homeostasis in vertebrates.
Unexpected role of inflammatory signaling in hematopoietic stem cell development: its role beyond inflammation.
Qiuping He,Feng Liu +1 more
TL;DR: Inflammatory signaling is not only an important regulator of HSCs in response to infection, but also plays a previously unrecognized role in HSC development in the absence of infection and inflammation.
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