Qingyu Wang
Pennsylvania State University
14 Papers
31 Citations
Qingyu Wang is an academic researcher from Pennsylvania State University. The author has contributed to research in topics: Drosophila melanogaster & Biology. The author has an hindex of 6, co-authored 9 publications.
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Papers
Complete Khoisan and Bantu genomes from southern Africa
Stephan C. Schuster,Webb Miller,Aakrosh Ratan,Lynn P. Tomsho,Belinda Giardine,Lindsay R. Kasson,Robert S. Harris,Desiree C. Petersen,Fangqing Zhao,Ji Qi,Can Alkan,Jeffrey M. Kidd,Yazhou Sun,Daniela I. Drautz,Pascal Bouffard,Donna M. Muzny,Jeffrey G. Reid,Lynne V. Nazareth,Qingyu Wang,Richard Burhans,Cathy Riemer,Nicola E. Wittekindt,Priya Moorjani,Elizabeth A. Tindall,Charles G. Danko,Wee Siang Teo,Anne M. Buboltz,Zhenhai Zhang,Qianyi Ma,Arno Oosthuysen,Abraham W. Steenkamp,Hermann Oostuisen,Philippus Venter,John P. Gajewski,Yu Zhang,B. Franklin Pugh,Kateryna D. Makova,Anton Nekrutenko,Elaine R. Mardis,Nick Patterson,Tom H. Pringle,Francesca Chiaromonte,James C. Mullikin,Evan E. Eichler,Ross C. Hardison,Richard A. Gibbs,Timothy T. Harkins,Vanessa M. Hayes +47 more
TL;DR: The extent of whole-genome and exome diversity among the five men, reporting 1.3 million novel DNA differences genome-wide, including 13,146 novel amino acid variants, suggests the Bushmen seem to be more different from each other than, for example, a European and an Asian.
Genetic diversity and population structure of the endangered marsupial Sarcophilus harrisii (Tasmanian devil).
Webb Miller,Vanessa M. Hayes,Vanessa M. Hayes,Aakrosh Ratan,Desiree C. Petersen,Desiree C. Petersen,Nicola E. Wittekindt,Jason R. Miller,Brian P. Walenz,James W. Knight,Ji Qi,Fangqing Zhao,Qingyu Wang,Oscar C. Bedoya-Reina,Neerja Katiyar,Lynn P. Tomsho,Lindsay Mc Clellan Kasson,Rae-Anne Hardie,Paula Woodbridge,Elizabeth A. Tindall,Mads F. Bertelsen,Dale Dixon,Stephen Pyecroft,Kristofer M. Helgen,Arthur M. Lesk,Thomas H. Pringle,Nick Patterson,Yu Zhang,Alexandre Kreiss,Gregory M. Woods,Menna E. Jones,Stephan C. Schuster +31 more
TL;DR: Analysis of 14 complete mitochondrial genomes from current and museum specimens, as well as mitochondrial and nuclear SNP markers in 175 animals, suggests that the observed low genetic diversity in today's population preceded the Devil Facial Tumor Disease disease outbreak by at least 100 y.
Quantitative Assessment of Eye Phenotypes for Functional Genetic Studies Using Drosophila melanogaster.
Janani Iyer,Qingyu Wang,Thanh Le,Lucilla Pizzo,Sebastian Grönke,Surendra S. Ambegaokar,Yuzuru Imai,Ashutosh Srivastava,Beatriz Llamusi Troísi,Graeme Mardon,Ruben Artero,George R. Jackson,Adrian M. Isaacs,Linda Partridge,Bingwei Lu,Justin P. Kumar,Santhosh Girirajan +16 more
TL;DR: The novel computational method developed, implemented as Flynotyper software, to quantitatively assess the morphological defects in the Drosophila eye resulting from genetic alterations affecting basic cellular and developmental processes will complement existing assays for eye phenotypes, and increase the accuracy of studies that use fly eyes for functional evaluation of genes and genetic interactions.
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Novel metrics to measure coverage in whole exome sequencing datasets reveal local and global non-uniformity.
TL;DR: Two novel metrics, Cohort Coverage Sparseness (CCS) and Unevenness (UE) Scores) are devised for a detailed assessment of the distribution of coverage of sequence reads in Whole Exome Sequencing (WES) data generated by three different platforms.
Novel metrics to measure coverage in whole exome sequencing datasets reveal local and global non-uniformity
TL;DR: Two novel metrics, Cohort Coverage Sparseness (CCS) and Unevenness (UE) Scores) are devised for a detailed assessment of the distribution of coverage of sequence reads in Whole Exome Sequencing (WES) data generated by three different platforms.