Qingwen Bai
Peking University
7 Papers
24 Citations
Qingwen Bai is an academic researcher from Peking University. The author has contributed to research in topics: Coacervate & Protocell. The author has an hindex of 4, co-authored 7 publications.
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Papers
Fission and Internal Fusion of Protocell with Membraneless "Organelles" Formed by Liquid-Liquid Phase Separation.
TL;DR: This study highlights that liquid-liquid phase separation of biopolymers is a powerful strategy to construct hierarchically structured protocells resembling the morphology and functions of living cells, and provides a step towards a better understanding of the transition mechanism from non-living to living matter under prebiotic conditions.
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Liquid-Liquid Phase Separation of Peptide/Oligonucleotide Complexes in Crowded Macromolecular Media.
TL;DR: In this paper, the authors investigated the phase separation processes in polyacrylamide (PAM) and poly(ethylene oxide) (PEO) media at varying concentrations and found that the droplet formation unit is the neutral primary complex, instead of individual S5 or ss-oligo.
23
Mass Transport in Coacervate-Based Protocell Coated with Fatty Acid under Nonequilibrium Conditions
TL;DR: This work prepares a hybrid protocell model by coating sodium oleate on the coacervate droplet constituted by poly(l-lysine) and oligonucleotide and investigates the transport of different molecules under electric field to make a step toward the nonequilibrium functionalization of synthetic protocells capable of biomimetic operations.
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Macromolecular Crowding and Confinement Effect on the Growth of DNA Nanotubes in Dextran and Hyaluronic Acid Media
Qiufen Zhang,Qingwen Bai,Lin Zhu,Tianhao Hou,Jiang Zhao,Dehai Liang +5 more
- 21 Jan 2020
TL;DR: This study demonstrates that the volume effect and noncovalent interactions are system specific and concentration dependent and governs the living processes in crowded cells.
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Crowding and Confinement Effects in Different Polymer Concentration Regimes and Their Roles in Regulating the Growth of Nanotubes
TL;DR: Among numerous research studies focusing on macromolecular crowding and confinement, few are concerned with the medium at a broad range of concentrations, let alone the interplay between the crowdi... as discussed by the authors.
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