Qing Xiao
Central South University
13 Papers
3 Citations
Qing Xiao is an academic researcher from Central South University. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 5, co-authored 8 publications.
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Papers
Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities
Jiaqi Liu,Qing Xiao,Jiani Xiao,Chenxi Niu,Yuanyuan Li,Xiaojun Zhang,Zheng-wei Zhou,Guang Shu,Gang Yin +8 more
TL;DR: In this paper , the authors comprehensively review the Wnt/β-catenin pathway from the above five aspects in combination with the latest research and propose challenges and opportunities for the development of small-molecular compounds targeting Wnt signalling pathway in disease treatment.
Downregulation of MEIS1 mediated by ELFN1-AS1/EZH2/DNMT3a axis promotes tumorigenesis and oxaliplatin resistance in colorectal cancer
Yimin Li,Yaqi Gan,Jiaxin Liu,Juanni Li,Zheng-wei Zhou,Ruotong Tian,Rui Sun,Jiaqi Liu,Qing Xiao,Yuanyuan Li,P. Lu,Yulong Peng,Yuqian Peng,Guang Shu,Gang Yin +14 more
TL;DR: In this article , the role of MEIS1 expression in oxaliplatin resistance was investigated in colorectal cancer (CRC) patients and the potential of therapeutics targeting ELFN1-AS1 and EZH2 in cell survival and oxali platin resistance, based on their controlling of MEis1 expression was highlighted.
MiR-221-3p targets ARF4 and inhibits the proliferation and migration of epithelial ovarian cancer cells.
Qihui Wu,Xiaolei Ren,Yimin Zhang,Xiaodan Fu,Yimin Li,Yulong Peng,Qing Xiao,Tong Li,Chunli Ouyang,Yixi Hu,Yu Zhang,Wenjuan Zhou,Wenguang Yan,Ke Guo,Wei Li,Yongbin Hu,Xiaojing Yang,Guang Shu,Haofan Xue,Zhangming Wei,Yonghong Luo,Gang Yin +21 more
TL;DR: The research uncovered the tumor suppressive role of miR-221-3p in EOC and directly targeted ARF4, suggesting that miR -221- 3p might be a novel potential candidate for clinical prognosis and therapeutics of EOC.
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Metformin suppresses the growth of colorectal cancer by targeting INHBA to inhibit TGF-β/PI3K/AKT signaling transduction
TL;DR: In this paper , the anti-proliferation effect of metformin was investigated in colorectal cancer patients, and it was shown that met-formin specifically suppressed the proliferation of CRC cells by causing G1/S arrest and attenuating TGF-β/PI3K/Akt signaling transduction.
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MicroRNA-222-3p/GNAI2/AKT axis inhibits epithelial ovarian cancer cell growth and associates with good overall survival.
Xiaodan Fu,Yimin Li,Ayesha B. Alvero,Juanni Li,Qihui Wu,Qing Xiao,Yulong Peng,Yongbin Hu,Xiang Li,Wenguang Yan,Ke Guo,Wenjuan Zhou,Yong Wang,Junwen Liu,Yu Zhang,Gil Mor,Jifang Wen,Gang Yin +17 more
TL;DR: It is found that higher expression of miR-222-3p was associated with better overall survival in EOC patients, and its level was negatively correlated with tumor growth in vivo, and the characterization of a novel regulatory axis in ovarian cancer cells, miR+3p/GNAI2/AKT is described.